by University of Turku Significantly increased amyloid accumulation at 55 years compared to 50 years after epilepsy onset compared to controls. Amyloid accumulation increased significantly more and in broader areas in the patient group during the follow-up period compared to controls. Credit: Neurology (2025). DOI: 10.1212/WNL.0000000000210303 Researchers have demonstrated that individuals who had childhood epilepsy have an increased...
Tag: <span>childhood epilepsy</span>
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New gene therapy could significantly reduce seizures in severe childhood epilepsy
by University College London CAMK2A-EKC therapy reduces seizure frequency. A. Timeline. B. Heatmap displaying seizure occurrence in each animal injected with either CAMK2A-GFP (gray) or CAMK2A-EKC virus (purple) before and after the treatment (virus injection on day 0). Crosses correspond to days where data acquisition was incomplete. C. Graph displaying the change in number of seizures...
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Researchers discover genetic variant associated with earlier onset childhood epilepsy
by Children’s Hospital of Philadelphia Credit: Unsplash/CC0 Public Domain Researchers at Children’s Hospital of Philadelphia (CHOP) have discovered a specific genetic variant in SCN1A, the most common genetic epilepsy, that leads to an earlier onset of epilepsy, with clinical features distinct from other epilepsies. The researchers also identified a potentially effective treatment strategy. The findings...