By Rachel Schraer Health reporter A drug that could stop cancer cells repairing themselves has shown early signs of working. More than half of the 40 patients given berzosertib had the growth of their tumours halted. Berzosertib was even more effective when given alongside chemotherapy, the trial run by the Institute of Cancer Research (ICR)...
by University Health Network Dr. Daniel De Carvalho and Krembil Brain Institute Medical Director Dr. Gelareh Zadeh collaborated to combine advanced technology with machine learning to develop a highly sensitive and accurate blood test to detect and classify brain cancers. Credit: UHN A simple but highly sensitive blood test has been found to accurately diagnose...
Computational modeling yields a protein fragment that could bind to coronavirus spike proteins and destroy them. The research described in this article has been published on a preprint server but has not yet been peer-reviewed by scientific or medical experts. Using computational models of protein interactions, researchers at the MIT Media Lab and Center for...
by University of Southern California A new study led by researchers at the USC Leonard Davis School of Gerontology is the first to demonstrate that a tiny protein has a big impact on health and longevity in both animals and humans. The researchers examined humanin, a peptide encoded in the small genome of mitochondria—the powerhouses...
by Baylor College of Medicine The epigenome is sometimes referred to as the “software” or “operating system” of the genome. It comprises small chemical modifications to DNA and the proteins that make up our chromosomes, and controls the activity of all the genes within the genome. During early life, as our organs develop, the epigenome...
by Newcastle University A regular dose of aspirin to reduce the risk of inherited bowel cancer lasts at least 10 years after stopping treatment, research has revealed. The international trial—known as CAPP2—involved patients with Lynch syndrome from around the world and revealed that two aspirins a day, for an average of two and a half...
By Rachel Schraer Health reporter A drug that could stop cancer cells repairing themselves has shown early signs of working. More than half of the 40 patients given berzosertib had the growth of their tumours halted. Berzosertib was even more effective when given alongside chemotherapy, the trial run by the Institute of Cancer Research (ICR)...
by University of Cambridge A new method of analyzing cancer patients’ blood for evidence of the disease could be up to ten times more sensitive than previous methods according to new research led by the University of Cambridge. In the coming years, this method and others based on this approach could lead to tests that...
Repairing a single mutation in the Tmc1 gene restored partial hearing in mice Key Findings: This is the first example of repairing a recessive gene mutation Repairing a single mutation in the Tmc1 gene restored partial hearing in mice The technique required the use of two viral vectors to deliver the base editing machinery Cells...
by National Cancer Institute Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient’s previous exposure to certain viruses. A study of the new approach was led...
