by Case Western Reserve University Candidate gene-targets of lincPRKD. (D) (top) Representative IHC images of RAD51B protein (brown staining) in primary gastric tumors, derived from tissue array (see Methods). The table at the bottom shows the number (and percentage) of gastric tumors with null, low-moderate, or high expression of RAD51B protein. Credit: Gastro Hep Advances (2025). DOI: 10.1016/j.gastha.2025.100618...
Tag: <span>gastric cancer</span>
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Gastric cancer biomarker nearly 90% accurate, even in early stages
By Paul McClure Researchers have identified a biomarker that can accurately diagnose gastric cancerDepositphotos Researchers have identified a blood protein that can be used as a marker of gastric and other cancers and is more accurate than existing diagnostic biomarkers, even in the early stages of the disease. The simple test may lead to the earlier...
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Scant Evidence for Proton Pump Inhibitor Role in Gastric Cancer
Laird Harrison January 12, 2023 The available evidence suggests that proton pump inhibitors (PPIs) do not cause gastric cancer, researchers say. The study could help resolve a controversy over one of the most serious side effects attributed to the widely used medications. “Our findings are reassuring, especially to all those patients who have an indication for long-term PPI use...
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Scant Evidence for Proton Pump Inhibitor Role in Gastric Cancer
Laird Harrison January 12, 2023 The available evidence suggests that proton pump inhibitors (PPIs) do not cause gastric cancer, researchers say. The study could help resolve a controversy over one of the most serious side effects attributed to the widely used medications. “Our findings are reassuring, especially to all those patients who have an indication for long-term PPI use...
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Scant Evidence for Proton Pump Inhibitor Role in Gastric Cancer
Laird Harrison January 12, 2023 The available evidence suggests that proton pump inhibitors (PPIs) do not cause gastric cancer, researchers say. The study could help resolve a controversy over one of the most serious side effects attributed to the widely used medications. “Our findings are reassuring, especially to all those patients who have an indication for long-term PPI use and...
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Magic traditional Chinese medicine ingredients generated autophagic flux to suppress tumor progression and novel combination therapy strategy in gastric cancer
SCIENCE CHINA PRESS IMAGE: ACTIVATION OF BECLIN-1 BY PICEATANNOL PROMOTES AUTOPHAGIC FLUX IN GC CELLS, AND COMBINED WITH EVEROLIMUS, TRIGGERS AUTOPHAGIC DEATH, ULTIMATELY INHIBITING TUMOR PROGRESSION, AND PROVIDING A NEW APPROACH TO GC TREATMENT. CREDIT: ©SCIENCE CHINA PRESS This study is led by Dr. Longtao Huangfu, and Dr. Xiaoyang Wang (Peking University Cancer Hospital &...
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Salvia miltiorrhiza extract is a potential preventive agent for gastric cancer induced by bile reflux
by Hong Kong Baptist University Conjugated BAs were highly associated with bile reflux gastritis. Human gastric sections and juice are analyzed in control (n = 50), BRG (n = 50), and GC (n = 45) groups. A) Representative images of EGD and H&E staining, bars, 50 µm. B) Heatmaps of normalized concentrations of the conjugated...
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Study reveals how gastric cancer forms, suggests preventive treatment
by Vanderbilt University Graphical abstract. Credit: Gastroenterology (2022). DOI: 10.1053/j.gastro.2022.06.021 A recently published study reveals new insights into how gastric cancer develops and suggests a preventive treatment. Eunyoung Choi, Ph.D., assistant professor of Surgery, and colleagues identified for the first time that Trop2+/CD133+/CD166+ dysplastic stem cellsare a key source of clonal evolution of dysplasia to multiple types of gastric cancer. Their investigation further...
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Gene variation may be early indicator for gastric cancer
by University of Arizona Graphical abstract. Credit: Gastroenterology (2022). DOI: 10.1053/j.gastro.2022.04.031 Researchers at the University of Arizona Health Sciences are hoping to catch stomach cancer before it develops in at-risk patients. In a paper published in Gastroenterology, researchers identified a genetic variation that could help identify when patients with Helicobacter pylori are more likely to develop stomach cancer....
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New preclinical models help identify stem cells that drive gastric cancer growth and spread
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR), SINGAPORE IMAGE: AN INVASIVE GASTRIC TUMOUR CONTAINING LGR5-EXPRESSING STEM-LIKE CELLS (GREEN), SOME OF WHICH ARE ACTIVELY PROLIFERATING (MAGENTA). ELIMINATION OF THESE TUMOUR-RESIDENT LGR5-EXPRESSING POPULATIONS GREATLY REDUCES TUMOUR GROWTH AND SPREAD IN MICE. CREDIT: SOWMYA SAGIRAJU AND GRACE LIM, INSTITUTE OF MOLECULAR AND CELL BIOLOGY (IMCB), A*STAR SINGAPORE – Scientists...