Arizona Sen. John McCain’s recent diagnosis of the hard-to-treat cancer glioblastoma stands in contrast to recent media reports that paint an optimistic picture of cancer treatment in America. A sampling of headlines includes “Cancer survival rates at all-time high” and “Cancer death rates continue to decrease in the United States.” Driving much of the progress...
Tag: <span>glioblastoma</span>
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Building a better blood-brain barrier model
Delivering drugs to the brain is no easy task. The blood-brain barrier -a protective sheath of tissue that shields the brain from harmful chemicals and invaders – cannot be penetrated by most therapeutics that are injected into a person’s blood stream. But for treating diseases of the central nervous system and cancers such as glioblastoma,...
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Brain cancer study reveals therapy clues
Researchers have pinpointed two key molecules that drive the growth of an aggressive type of adult brain cancer. The findings shed light on the mechanisms that underpin brain cancer progression and could eventually reveal targets for the development of much-needed therapies, researchers say. Lab tests Scientists conducted lab tests on tumour cells from patients with glioblastoma, a rare but...
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Results of glioblastoma clinical trial show safety and clinical benefit of CAR T cell therapy
Glioblastoma is the most common brain tumor in humans and also one of the most difficult cancers to treat; patients with this type of cancer only survive about one year from time of diagnosis. Researchers at Baylor College of Medicine, Texas Children’s Cancer Center, and the Center for Cell and Gene Therapy at Baylor, Texas...
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Stem cells beat the clock for brain cancer
New research has shown that human skin cells can be transformed into stem cells, and used to hunt down brain cancer Glioblastoma is an aggressive form of brain cancer that kills most patients within two years of diagnosis. In tests on mice last year, a team at the University of North Carolina at Chapel Hill...
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Revolutionary approach for treating glioblastoma works with human cells
Revolutionary approach for treating glioblastoma works with human cells (Chapel Hill, N.C. – Feb. 1, 2017) — In a rapid-fire series of breakthroughs in just under a year, researchers at the University of North Carolina at Chapel Hill have made another stunning advance in the development of an effective treatment for glioblastoma, a common and...
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Immunotherapy, gene therapy combination shows promise against glioblastoma
“Devastating” and “dismal.” That’s how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months. New research out of the University of Michigan supports combining two approaches to fight back against gliomas: attacking the tumor with gene therapy while...
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Salmonella Used To Attack Fatal Brain Tumors In Rats
Salmonella does not exactly enjoy a good reputation as it is deemed pathogenic and often implicated in food poisoning cases. But what happens when you recruit the bacterial strain in the mission to kill tumors? Scientists from Duke University genetically tweaked salmonella to help scour and destroy tumors, a development that can potentially help fight the...