by University of Illinois at Chicago Overall schematic of HPSE-mediated neuroinflammation. After HSV-1 infection, HPSE was involved in cascade of events leading to inflammasome formation and caspase activation along with proinflammatory cytokine upregulation and gasdermin-mediated cell death. The above series of events leads to neuroinflammation and cell death. Credit: mBio (2025). DOI: 10.1128/mbio.03765-24 Herpes simplex virus-1 (HSV-1) is...
Tag: <span>herpes infections</span>
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Tweak to pritelivir allows treatment of latent herpes infections
by Bob Yirka , Medical Xpress Credit: CC0 Public Domain A team of researchers at Innovative Molecules GmbH, working with several other institutions in Germany, has developed a small-molecule therapy for the treatment of latent herpes simplex virus infections. In their paper published in the journal Science Translational Medicine, the group describes tweaking a drug used for treating...
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Researchers pursuing novel treatments for herpes infections and diabetes win STAT Madness
By Rebecca Sohn April 5, 2021 Martine Aubert, left, and Keith Jerome of the Fred Hutchinson Cancer Research Center led one of the teams that won STAT Madness. FRED HUTCHINSON CANCER RESEARCH CENTER From curing herpes to treating diabetes in a new way, their innovations might one day treat some of the world’s most prevalent health...