by Washington University School of Medicine HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia Treatment for HIV has improved tremendously over the past 30 years; once a death sentence, the disease is now a manageable lifelong condition in many parts of the world. Life expectancy is about the same as that of individuals without HIV, though patients must...
by H. Lee Moffitt Cancer Center & Research Institute Intermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) and mucinous epithelium that pseudo-stratifies (left – diagnostic of a LMP tumour). Epithelium in a frond-like architecture is seen at the top of image. Credit: Nephron /Wikipedia. CC...
Macrophages – immune cells that both fight infections and fix the damage they cause – are often placed into two categories: those that increase inflammation (known as “M1”) to attack, and those that decrease inflammation to begin the healing process (“M2”). Researchers in the lab of Kathryn Miller-Jensen, associate professor of biomedical engineering and molecular,...
Special immune cells found in the brain, microglia, play a key role in the processes that make you feel uneasy and depressed in correlation with inflammation. The findings from a new study on mice suggest that microglial cells contribute to the negative mood experienced during several neurological diseases. Image credit: Pixabay (Free Pixabay license) David...
by Medical College of Georgia at Augusta University Drs. Babak Baban (foreground) and Krishnan Dhandapani. Credit: Kim Ratliff, Augusta University photographer Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report. They...
by Max Delbrück Center for Molecular Medicine Previously only suspected, now made it visible thanks to the molecular reporter: where human tumor cells and brain cells of a mouse meet, the tumor cells have a different identity than everywhere else (green). Credit: Gargiulo Lab, MDC Glioblastoma is the most common malignant brain tumor in adults. Roughly...
by The Francis Crick Institute Dendritic cells are white blood cells that get their name from their tree-like shape. Credit: The Francis Crick Institute Researchers at the Francis Crick Institute have uncovered an important process in how our immune system detects signs of disease and activates a protective response. This understanding could improve efforts to find new...
Daniela Latorre wanted to be a scientist since she was a child. At the Institute for Research in Biomedicine, affiliated to the USI in Bellinzona and the Institute of Microbiology, she is finding evidence that narcolepsy is an autoimmune disease. She has now received the Pfizer Prize for Research 2020 for her pioneering work. “This is my very first...
by Julie Langelier, Gladstone Institutes Credit: CC0 Public Domain An important part of the brain’s immune system, cells called microglia constantly extend and retract “branches” from their cell body to survey their environment. Think of an octopus, not moving its body, but reaching its tentacles in every direction. That’s how microglia operate. In the span of...
by Steven Schultz, Princeton University In this artist’s rendering, a component of the human immune system known as a T cell, in the lower left position, attacks a cancer cell, upper right. Credit: Lim Lab One of the most promising new cancer therapies involves engineering cells from the body’s own immune system to attack tumors, but...
