The term Regenerative Medicine covers so much biomedical science these days including everything from just about any kind of cell therapy (not just stem cells) to CRISPR gene editing, and with the the COVID-19 pandemic, it seems this umbrella use of the term now includes potential treatment of viral illnesses. It can be hard to...
Senescence is a hallmark of cellular ageing and contributes to many diseases. A new method enabling immune cells to target senescent cells might offer improved therapeutic options. Senescence is a form of cellular stress response. In some circumstances it can be harmful, and efforts are under way to develop therapies that target senescent cells. Writing...
UNIVERSITY OF CALIFORNIA – SAN DIEGO Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce. The first data describing this new direction for fighting COVID-19 were published on June...
by Rockefeller University Press A phase I/II clinical trial by researchers at Stanford University suggests that vaccines prepared from a patient’s own tumor cells may prevent the incurable blood cancer mantle cell lymphoma (MCL) from returning after treatment. The study, which will be published June 19 in the Journal of Experimental Medicine (JEM), reveals that...
by Luxembourg Institute of Health Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) have developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby modulating the levels of opioid peptides produced in the central nervous system (CNS) and potentiating...
Study shows nervous and immune systems ‘need to talk’ for bone repair Photomicrographs from a recent Johns Hopkins Medicine study showing the importance of the peripheral nervous system in bone injury repair. Clockwise from bottom left: (A) Micro computed tomography image showing bone regrowth in mouse skull 14 days after injury (dashed black line is...
by Salk Institute A significant site of damage during COVID-19 infection is the lungs. Understanding how the lungs’ immune cells are responding to viral infections could help scientists develop a vaccine. Now, a team of researchers led by Salk Professor Susan Kaech has discovered that the cellsresponsible for long-term immunity in the lungs can be...
by Rockefeller University Press Researchers at Wake Forest School of Medicine have discovered that nicotine promotes the spread of lung cancer cells into the brain, where they can form deadly metastatic tumors. The study, which will be published June 4 in the Journal of Experimental Medicine (JEM), suggests that nicotine replacement therapies may not be...
by Medical College of Georgia at Augusta University A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report....
by VIB (the Flanders Institute for Biotechnology) With a discovery that could rewrite the immunology textbooks, an international group of scientists, including the teams of Bart Lambrecht, Martin Guilliams, Hamida Hammad, and Charlotte Scott (all from the VIB-UGent Center for Inflammation Research) identified a new type of antigen-presenting immune cell. These cells, that are part...
