by University of Freiburg Only within the past few years has malignant melanoma been treatable with immunotherapy. However, in every second patient, strong autoimmune reactions such as skin rash or diarrhea occur after immunotherapy. Researchers from the Medical Center—University of Freiburg and Swiss colleagues have now shown that these reactions can be stopped with a...
Tag: <span>Immune cells</span>
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Specialized immune cells could help repair inflammatory bowel disease damage in children
UNIVERSITY OF BRITISH COLUMBIA A new study suggests that specialized immune cells that dampen inflammation and help repair the gut could be used as a potential therapy for children dealing with the painful symptoms of inflammatory bowel disease (IBD). The research from BC Children’s Hospital and the University of British Columbia shows that a specific...
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Cancer researchers discover how immune cells avoid killing themselves
By Michael Irving We have a lot to thank our immune systems for, as they remain ever-vigilant to protect us from cancer and infections. But exactly how do immune cells avoid wiping themselves out while attacking invaders? Researchers at Australia’s Peter MacCallum Cancer Centre and the University College London (UCL) have now found that they...
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Vaping wrecks immune cell function, increases infection risk
By Dr. Liji Thomas, MDNov 17 2019 A new study published in the Journal Cell Physiology shows that e-cigarettes have toxic effects on neutrophils function, making them a threat to human health by increasing the likelihood of infection with Gram-negative bacteria. E-cigarettes are in wide use today, among 7% to 12% of adults and up to 37% of...
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‘EATER CELLS’ MAY PREVENT EVEN WORSE DAMAGE AFTER HEART ATTACK
POSTED BY JULIA EVANGELOU STRAIT-WUSTL Boosting the activity of specific immune cells in the heart after a heart attack can protect against developing heart failure, according to research with mice. Patients with heart failure, an invariably fatal condition, tire easily and become breathless from everyday activities because the heart muscle has lost the ability to pump...
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Why beta-blockers cause skin inflammation
University study finds possible cause of a known phenomenon UNIVERSITY OF BONN Beta-blockers are often used to treat high blood pressure and other cardiovascular diseases. However, in some patients they can trigger or exacerbate psoriasis, an inflammatory skin disease. Scientists at the University of Bonn and Freie Universität Berlin have now found a possible cause...
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Early Results from First-In-U.S. Trial of CRISPR-Edited Immune Cells for Cancer Patients Suggest Safety of Approach
Abramson Cancer Center researchers to present initial safety data after treating three patients. Genetically editing a cancer patient’s immune cells using CRISPR/Cas9 technology, then infusing those cells back into the patient appears safe and feasible based on early data from the first-ever clinical trial to test the approach in humans in the United States. Researchers...
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Enter the exosome: WVU researcher studies how cancer and immune cells communicate
WEST VIRGINIA UNIVERSITY Cells can’t text each other the way we can, but they can still communicate. One way they send each other messages is through exosomes–tiny, spherical “packages” of information they emit. David Klinke, a researcher with the West Virginia University School of Medicine and Cancer Institute, is deciphering the contents of exosomes that...
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Study reveals more about how immune cells create new types of antibodies
by Bob Yirka , Medical Xpress A team of researchers at Boston Children’s Hospital has learned more about the process of V(D)J recombination and how it makes use of chromatin looping to collect segments that are to be spliced. In their paper published in the journal Nature, the researchers outline their research and what they...
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Moffitt researchers identify a mechanism controlling tumor cell recognition by immune cells
The STING signaling pathway induces an inflammatory response and tumor cell recognition H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. (Nov. 1, 2019) – Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma. However, tumors can escape immune cell detection even with the use of immunotherapies. In a...