WEST VIRGINIA UNIVERSITY Cells can’t text each other the way we can, but they can still communicate. One way they send each other messages is through exosomes–tiny, spherical “packages” of information they emit. David Klinke, a researcher with the West Virginia University School of Medicine and Cancer Institute, is deciphering the contents of exosomes that...
Tag: <span>Immune cells</span>
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Study reveals more about how immune cells create new types of antibodies
by Bob Yirka , Medical Xpress A team of researchers at Boston Children’s Hospital has learned more about the process of V(D)J recombination and how it makes use of chromatin looping to collect segments that are to be spliced. In their paper published in the journal Nature, the researchers outline their research and what they...
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Moffitt researchers identify a mechanism controlling tumor cell recognition by immune cells
The STING signaling pathway induces an inflammatory response and tumor cell recognition H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. (Nov. 1, 2019) – Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma. However, tumors can escape immune cell detection even with the use of immunotherapies. In a...
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The night gardeners: Immune cells rewire, repair brain while we sleep
UNIVERSITY OF ROCHESTER MEDICAL CENTER Science tells us that a lot of good things happen in our brains while we sleep – learning and memories are consolidated and waste is removed, among other things. New research shows for the first time that important immune cells called microglia – which play an important role in reorganizing...
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Study fingers new player in cancer immunity
Deleting immune-regulatory gene boosted tumor-fighting capacity in the immune cells of mice with colon cancer, melanoma HARVARD MEDICAL SCHOOL The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body’s healthy tissues and organs. This balancing feat is accomplished by...
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These secret battles between your body’s cells might just save your life
To fight cancer and ageing, biologists are looking at how cells evict, kill or cannibalize less-fit rivals. Kendall Powell Yasuyaki Fujita has seen first-hand what happens when cells stop being polite and start getting real. He caught a glimpse of this harsh microscopic world when he switched on a cancer-causing gene called Ras in a few kidney cells in a dish....
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Blocking a hormone’s action in immune cells may reduce heart disease risk
by American Physiological Society Blocking the mineralocorticoid receptor (MR)—a protein that helps maintain normal levels of salt and water in the body—in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health. The study will be presented today at the American Physiological Society (APS) Aldosterone and ENaC in...
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Parkinson’s disease is also present in the blood
by Aarhus University The behaviour of immune cells in the blood is so different in patients with Parkinson’s disease that it advocates for a new type of supplementary medicine, which can regulate the immune system and thus inhibit the deterioration of the brain. These are the perspectives in a new study which researchers from the...
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Genomic map implicates broad immune cell involvement in multiple sclerosis
COLUMBIA UNIVERSITY IRVING MEDICAL CENTER The International Multiple Sclerosis Genetic Consortium (IMSGC) reports the results of its latest study, “Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility”, in the journal Science today: the highly productive collaborative group presents a new milestone in its efforts to understand the genetic basis of multiple...
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Synthetic cells capture and reveal hidden messages of the immune system
by University of Oxford When immune cells detect harmful pathogens or cancer, they mobilise and coordinate a competent defence response. To do this effectively immune cells must communicate in a way that is tailored to the pathogenic insult. Consequently, the body’s response to various health challenges depends on successful coordination among the cells of the immune...