UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: “PRECISE BLOOD VESSEL FUNCTION IS CRITICAL TO ACCOMMODATE THE EXTREME ENERGY DEMANDS OF THE BRAIN FOR NORMAL BRAIN FUNCTION,” SAID UKPONG B. EYO, PH.D., OF UVA’S DEPARTMENT OF NEUROSCIENCE, THE UVA BRAIN INSTITUTE, AND UVA’S CENTER FOR BRAIN IMMUNOLOGY AND GLIA (BIG). “THESE FINDINGS SUGGEST PREVIOUSLY UNKNOWN ROLES FOR...
Tag: <span>Immune cells</span>
Altering metabolism in immune cells helps damaged nerves recover
by Johns Hopkins University School of Medicine Photograph from a Johns Hopkins Medicine study showing regenerated junctions between peripheral nerves and their muscle fibers in mice. By modifying white blood cells known as macrophages, Johns Hopkins Medicine researchers were able to achieve complete recovery from injury to the nerves. Credit: Mithilesh Kumar Jha, Johns Hopkins Medicine Peripheral nerves—the...
Right program could turn immune cells into cancer killers
IMAGE: A TUMOR-SPECIFIC T CELL ENGAGES WITH A TUMOR CELL. BYSTANDER T CELLS DO NOT ENGAGE WITH THE TUMOR. CREDIT: PNAS DEC. 10, 2002, COPYRIGHT (2002) NATIONAL ACADEMY OF SCIENCES, U.S.A. Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different “program” that...
Discovery highlights the complex lifestyles of frontline immune cells
by Walter and Eliza Hall Institute WEHI researcher Dr Michael Chopin have made a surprise discovery about how immune ‘sentinel’ cells are maintained, which could have implications for drugs in development for treating cancer. Credit: WEHI WEHI researchers have made a surprise discovery about how immune ‘sentinel’ cells are maintained, which could have implications for drugs in development...
A specific subset of immune cells that mitigates kidney damage
by Ludwig Maximilian University of Munich Immunfluorescence of mononuclear phagocytes in the murine kidney. Credit: Barbara Schraml, Stephan Rambichler; LMU The immune system is highly complex. For example, a particular class of cells called mononuclear phagocytes (MNPs) plays important roles in the uptake and disposal of damaged cells, the elimination of invasive pathogens and other foreign...
Right program could turn immune cells into cancer killers
by Amy Mone, Johns Hopkins University A tumor-specific T cell engages with a tumor cell. Bystander T cells do not engage with the tumor. Credit: PNAS Dec. 10, 2002, Copyright (2002) National Academy of Sciences Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different “program”...
Turning immune cells into killers
by University of Würzburg Liver tissue with innate lymphoid cells (ILCs), visualised here as red dots. Credit: Ye Ouyang / University of Wuerzburg When pathogens invade the human body, a rapid response is required. At the forefront of the immune response are special immune cells. They reside in various tissues such as the lungs, liver, skin...
Study reveals how immune cells can be trained to fight infections
by Stuart Wolpert and Todd Schindler, University of California, Los Angeles In this image from a microscopy video, scientists track the activity of NFκB inside the cell as it responds to a stimulus. Credit: Brooks Taylor/UCLA The body’s immune cells naturally fight off viral and bacterial microbes and other invaders, but they can also be reprogrammed...
Immune cells in the human biliary system mapped
by Karolinska Institutet Credit: Pixabay/CC0 Public Domain Researchers at Karolinska Institutet in Sweden have analyzed and described in detail the immune cells residing in the human bile duct. The findings may pave the way for new treatment strategies against disorders of the bile duct, which are often linked to immunological processes. The study is published in the...
Start-stop system of hunting immune cells
by Max Planck Society Neutrophils (green) form cell swarms and accumulate at tissue sites where they need to contain damaged cells or invading microbes. Multicolored trajectories of neutrophil migration paths are displayed. Credit: MPI of Immunobiology & Epigenetics/ T. Lämmermann Neutrophils belong to the first responders of our immune system. They circulate in our bodies and...