By Sally Robertson, B.Sc. Researchers at the University of Washington in Seattle have conducted a study suggesting that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can directly infect heart tissue and contribute to whole-organ cardiac dysfunction. Charles Murry and colleagues found that the virus directly infected cardiomyocytes, impaired their electrophysiological and contractile properties,...
Tag: <span>inflammation</span>
Fat crystals trigger chronic inflammation
Scientists at the University of Bonn identify previously unknown disease mechanism UNIVERSITY OF BONN DEOXYSPHINGOLIPIDS (GREEN) INTERFERE NOT ONLY WITH THE WORK OF THE MITOCHONDRIA (RED) BUT ALSO WITH CELL DIVISION. SOME OF THEM THEREFORE HAVE TWO NUCLEI (TURQUOISE). view more CREDIT: © AG KÜRSCHNER/UNIVERSITÄT BONN A congenital disorder of the fat metabolism can apparently...
World-first study on blood hormone could reduce cardiovascular deaths
by Kim Thomas, University of Otago A simple blood test could identify seemingly-healthy people with a high hidden risk of heart disease thanks to a world-first discovery by University of Otago, Christchurch researchers. Researchers from the University’s Christchurch Heart Institute studied the blood samples and cardiology scans of 665 healthy young and middle-aged people with...
Concussions can cause long-term sleep problems
by Norwegian University of Science and Technology A new study shows that people who have had concussions sometimes develop long-term after effects, including sleep disturbances. The findings could also be of use to other patient groups. Every year, thousands of people end up in the emergency room or hospital with minor head injuries, often diagnosed...
Childhood syndrome linked to COVID-19 causes profound immune changes
NATIONAL INSTITUTE FOR HEALTH RESEARCH Researchers have uncovered how the immune system is altered in a rare COVID-19 related illness in children referred to as paediatric inflammatory multisystem syndrome (PIMS-TS). PIMS-TS is a rare syndrome which has emerged in a small number of children during the COVID-19 pandemic. The condition causes severe inflammation in blood...
Protein produced by the nervous system may help treatments for inflammatory diseases
Rutgers researchers discovered a new role the protein may have in helping to treat allergies, asthma, COPD RUTGERS UNIVERSITY A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD). In a study published in the journal Nature Immunology, researchers discovered that neuromedin...
Discovery of natural compound may help fend off antibiotic resistance of hard-to-treat infections
The Vanderbilt Laboratory for Biosynthetic Studies, led by Brian Bachmann, professor of chemistry, has discovered a naturally occurring compound that is resilient to antibiotic resistance because of its rare properties. Antibiotic resistance, the ability of bacteria to evade antibiotic treatment, has been identified by the Centers for Disease Control and Prevention as one of the...
Dietary control of the healing of injury-induced inflammation
This article by Dr. Barry Sears and colleagues is published in Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2020 BENTHAM SCIENCE PUBLISHERS Injuries induce the initiation of inflammation to control the damage. However, the resolution of the injury-induced inflammation leading to healing is not well characterized. This new article by researchers at the Inflammation Research...
Study reveals immune-system paralysis in severe COVID-19 cases
by Stanford University Medical Center 3D print of a spike protein of SARS-CoV-2, the virus that causes COVID-19–in front of a 3D print of a SARS-CoV-2 virus particle. The spike protein (foreground) enables the virus to enter and infect human cells. On the virus model, the virus surface (blue) is covered with spike proteins (red)...
Researchers characterize important regulators of tissue inflammation, fibrosis and regeneration
Therapeutic manipulations of these cells hold promise for promoting muscle injury repair and improving outcomes for individuals with muscular dystrophy (Boston)– Although macrophages (cells involved in the detection and destruction of bacteria and other harmful organisms as well as dead cells) are classified as immune cells functioning in the activation and resolution of tissue inflammation,...