By Sally Robertson, B.Sc Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19). The scientists propose that the antiviral and...
Researchers from Sechenov University (a Project 5-100 participant) and University of Pittsburgh (USA) discovered that the resistance of innate immune cells, macrophages, to ferroptosis – a type of programmed cell death – depends on the type of their activation. It turned out that cells helping tissues to recover from inflammation were more vulnerable. The researchers...
UNIVERSITY PARK, Pa. — Adding an array of spices to your meal is a surefire way to make it more tasty, but new Penn State research suggests it may increase its health benefits, as well. In a randomized, controlled feeding study, the researchers found that when participants ate a meal high in fat and carbohydrates...
by Aston University Scientists have discovered a new treatment to dramatically reduce swelling after brain and spinal cord injuries, offering hope to 75 million victims worldwide each year. The breakthrough in treating such injuries—referred to as central nervous system (CNS) edema—is thought to be hugely significant because current options are limited to putting patients in...
he barrier between mind and body appears to be crumbling. Clinical practice and public perception need to catch up. The GuardianEdward Bullmore Unlikely as it may seem, #inflammation has become a hashtag. It seems to be everywhere suddenly, up to all sorts of tricks. Rather than simply being on our side, fighting infections and healing...
Already known for their shape-shifting abilities, stem cells can now add “death-defying” to their list of remarkable qualities. A new study shows how stem cells – which can contribute to creating many parts of the body, not just one organ or body part – are able to postpone their own death in order to respond...
Durham, NC – Infection, inflammation, trauma, disease, contact lenses – all of these and more can lead to corneal scarring, which according to the World Health Organization is a leading cause of blindness worldwide. While corneal transplant remains the gold standard to treat this condition, patient demand far outweighs donor supply. However, in a study...
by Fritz Lipmann Institute on the proteome of the intestinal epithelium and leads to age-related impairments in adaptation to nutrient availability. (Source: FLI / Alessandro Ori & Nadja Gebert. Created with BioRender.com) The small intestine is one of the most important interfaces between the environment and our body. It is responsible for nutrient absorption but...
LA JOLLA–(May 1, 2020) Salk and Scripps Research Institute scientists, along with collaborators at the pharmaceutical company Lundbeck, identified two genes that can regulate levels of healthy fats, called FAHFAs, in mice. The team found that the loss of the two genes led to higher-than-normal levels of the beneficial FAHFAs, while blocking the genes’ activity...
April 20, 2020–New guidance is available for physicians who must go through a number of steps to provide a probable diagnosis of sarcoidosis – an inflammatory disease that affects the lungs, lymph glands, and other organs. The American Thoracic Society has published an official clinical practice guideline in which a panel of experts strongly recommended...
