FLINDERS UNIVERSITY Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases. The study in Redox Biology describes how fibrinogen can be protective against hypochlorite – a chemical generated by the body during inflammation – and so act as a kind...
Tag: <span>inflammation</span>
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A Closer Look at How Immune Cells Attack and Heal
Macrophages – immune cells that both fight infections and fix the damage they cause – are often placed into two categories: those that increase inflammation (known as “M1”) to attack, and those that decrease inflammation to begin the healing process (“M2”). Researchers in the lab of Kathryn Miller-Jensen, associate professor of biomedical engineering and molecular,...
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Immune cells are behind the depression experienced in inflammation
Special immune cells found in the brain, microglia, play a key role in the processes that make you feel uneasy and depressed in correlation with inflammation. The findings from a new study on mice suggest that microglial cells contribute to the negative mood experienced during several neurological diseases. Image credit: Pixabay (Free Pixabay license) David...
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CT identifies patients with high-risk nonalcoholic fatty liver disease (NAFLD)
AMERICAN ROENTGEN RAY SOCIETY IMAGE: A and B, True-positive assessments in 58-year-old woman (A) and 52-year-old man (B) with high-risk NAFLD and associated NASH. CT images show hepatic enlargement, heterogeneously low-attenuation hepatic parenchyma, and surrounding ascites. Readers correctly identified NASH according to these imaging features. Readers also correctly identified fibrosis stage F3. C and D,...
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Newly discovered subset of brain cells fight inflammation with instructions from the gut
by Brigham and Women’s Hospital Credit: Unsplash/CC0 Public Domain Astrocytes are the most abundant type of cells within the central nervous system (CNS), but they remain poorly characterized. Researchers have long assumed that astrocytes’ primary function is to provide nutrients and support for the brain’s more closely scrutinized nerve cells; over the years, however, increasing evidence has shown...
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New research finds connection: Inflammation, metabolism and scleroderma scarring
MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN Scleroderma, a chronic and currently incurable orphan disease where tissue injury causes potentially lethal skin and lung scarring, remains poorly understood. However, the defining characteristic of systemic sclerosis, the most serious form of scleroderma, is irreversible and progressive scarring that affects the skin and internal organs. Published in iScience, Michigan Medicine’s Scleroderma...
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Inflammation from ADT may cause fatigue in prostate cancer patients
Moffitt Cancer Center study suggests elevation in inflammation marker IL-6 linked to higher levels of fatigue H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. — Prostate cancer is one of the most common cancers among men in the U.S. For many patients, hormone therapy is a treatment option. This type of therapy, also called androgen...
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Study: e-cigarettes trigger inflammation in the gut
Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: IN THE BOTTOM FRAMES, BURST CELL JUNCTIONS IN THE GUT LINING CAN BE SEEN AFTER BEING EXPOSED TO E-CIGARETTE CHEMICALS AS COMPARED TO HEALTHY CELLS...
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The two sides of inflammation—the cure and the curse
by Delthia Ricks , Medical Xpress Credit: Pixabay/CC0 Public Domain One of the many wonders—and mysteries—of human biology is the complex response of the innate immune system, which is known for its swiftness in annihilating invading pathogens and capacity to mount an explosive inflammatory response. The body’s ability to rapidly sense and react to infiltrating...
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Cognitive behavior therapy the best non-drug treatment for inflammation, study shows
(Credit: cottonbro from Pexels)December 24, 2020Health & Medical, Psychological by Craig T Lee Share Tweet LOS ANGELES — People are usually quick to go straight to medication to reduce chronic inflammation, but that isn’t always healthiest choice for everyone. A study finds there may be a surprising way to ease these symptoms without using drugs — therapy. Researchers from UCLA,...