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Insulin Resistance: Your Questions Answered
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Insulin Resistance: Your Questions Answered

BY AMY CAMPBELL, MS, RD, LDN, CDCES | JUNE 7, If you’ve watched television lately, you might have seen ads for supplements and diet plans claiming to reverse insulin resistance and help you lose weight. The term “insulin resistance” has been trending in the media for a while now, and it might be hard to figure out what...

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Higher Vitamin D3 Levels Link to Less Insulin Resistance

Marlene Busko, for Medscape March 24, 2022 Researchers published the study covered in this summary on Research Square as a preprint that has not yet been peer reviewed. Key Takeaways Data from five sequential National Health and Nutrition Examination Survey (NHANES) reports using US population samples in 2009-2018 showed each 1-unit increase in serum levels of vitamin D3 (25-hydroxyvitamin...

Even moderate light exposure during sleep harms heart health and increases insulin resistance: study
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Even moderate light exposure during sleep harms heart health and increases insulin resistance: study

by Northwestern University Credit: Pixabay/CC0 Public Domain Close the blinds, draw the curtains and turn off all the lights before bed. Exposure to even moderate ambient lighting during nighttime sleep, compared to sleeping in a dimly lit room, harms your cardiovascular function during sleep and increases your insulin resistance the following morning, reports a new...

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Senolytic Treatment Minimizes the Contribution of Excess Fat Tissue to Insulin Resistance in Mice

Senescent cells accumulate with age throughout the body, and contribute directly to the onset and progression of a wide range of age-related conditions. While never present in large numbers in comparison to normal somatic cells, senescent cells are metabolically active, secreting signals that provoke chronic inflammation, altered cell behavior, and numerous forms of tissue dysfunction....

Signaling molecules called EETs may improve treatment for insulin resistance
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Signaling molecules called EETs may improve treatment for insulin resistance

by Bill Snyder, Vanderbilt University Medical Center Credit: CC0 Public Domain Analogs of signaling molecules called EETs may improve treatment of insulin resistance, a primary risk factor for development of Type 2 diabetes and cardiovascular disease, according to a new paper by researchers at Vanderbilt University Medical Center. Ambra Pozzi, Ph.D., and colleagues previously reported that EETs...

Researchers identify potential cause and treatment for obesity and insulin resistance
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Researchers identify potential cause and treatment for obesity and insulin resistance

by  Monash University Credit: Shutterstock Monash University researchers have shown for the first time that mesenteric (gut) lymphatic dysfunction is a potential cause of and therapeutic target for obesity and insulin resistance. The groundbreaking study, published in Nature Metabolism, identified a profoundly damaging cycle in which a high fat diet promotes dysfunction of the mesenteric lymphatics, that in turn leads to...

Differences in cellular signaling offer clues to insulin resistance
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Differences in cellular signaling offer clues to insulin resistance

by Max Bingham,  Harvard Medical School Credit: Pixabay/CC0 Public Domain In what could be a starting point for new therapeutics to tackle insulin resistance, a major driver of type 2 diabetes and metabolic syndrome present in 20–30 percent of the general U.S. population, researchers recently found that insulin resistance in the general population seems likely to be caused...

Blocking a protein in liver cells protects against insulin resistance, fatty liver disease
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Blocking a protein in liver cells protects against insulin resistance, fatty liver disease

by  University of California, Los Angeles Mitochondria inside liver cells (hepatocytes). Credit: Mayuko Segawa, Liesa lab at UCLA Health A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice....

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Connecting the dots between insulin resistance, unhealthy blood vessels and cancer

Animal studies examine risk factors that may overlap between colorectal cancer and cardiovascular disease Christian Rask-Madsen, M.D., Ph.D., is assistant investigator in the Section on Vascular Biology and Complications at Joslin Diabetes Center, and assistant professor at Harvard Medical School. Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone...

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