Peer-Reviewed Publication Xia & He Publishing Inc. FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail Backgrounds and objectives Gastrointestinal complications are common in patients after ischemic stroke. Gastric motility is regulated by gastric pace-making activity (also called gastric myoelectrical activity (GMA)) and autonomic function. The aim of this study was to evaluate GMA, assessed by noninvasive electrogastrography (EGG), and autonomic function, measured...
Tag: <span>ischemic stroke</span>
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FDA Okays Tenecteplase for Acute Ischemic Stroke
Megan Brooks March 04, 2025 197 The US Food and Drug Administration (FDA) has approved the thrombolytic tenecteplase (TNKase, Genentech) for treatment of acute ischemic stroke in adults. The drug is administered as a single, 5-second intravenous bolus — a faster and simpler administration compared to the standard of care 60-minute infusion of alteplase (Activase; Genentech), the manufacturer said in a news...
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Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise
by Juntendo University Research Promotion Center GPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neurological deficits and blood-brain barrier disruption. These findings offer insights into developing innovative clinical approaches for ischemic stroke. Credit: Dr. Airi Jo-Watanabe of Juntendo University Graduate School of MedicineCells actively rely on maintaining an...
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Study shows blood test can predict functional outcome after ischemic stroke
by University of Gothenburg Credit: CC0 Public DomainResearchers from from the University of Gothenburg have developed an ultra-sensitive blood test that reflects brain damage after acute ischemic stroke—and also predicts functional outcome. This is a discovery that is expected to be of great significance in the future. The findings are described in the journal Neurology. The...
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Study: A novel cell-penetrating peptide exerts therapeutic effects against ischemic stroke
by Sichuan International Medical Exchange and Promotion Association The Tat-SIRT5-CTM peptide specifically blocked the interaction of SIRT5 with ANXA1, led to SIRT5 degradation and thereby inhibiting SIRT5-mediated desuccinylation of ANXA1, which in turn alleviated microglia-induced neuroinflammation, and eventually improved the survival of neurons subjected to cerebral ischemia and reperfusion injury. Credit: Figure was drawn using...
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A new mechanism encouraging the brain to self-repair after an ischemic stroke
by Tokyo Medical and Dental University The neurons around an injured brain region will play major roles in promoting functional recovery through nervous system development, synapse organization, and remyelination; however, the molecular mechanisms triggering such a broad range of neural repair after brain injury remained unknown. Our study demonstrated that the secretion of PLA2G2E from perilesional...
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Both men and women who experience migraines carry an increased risk of ischemic stroke
by Public Library of Science Migraine. Credit: Colourbox.dk/Andrea De Martin (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) Women and men who experience migraine headaches also carry an elevated risk of having an ischemic stroke, but women alone may carry an additional risk of heart attack and hemorrhagic stroke, according to a new study led by Cecilia Hvitfeldt Fuglsang of Aarhus University,...
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Clinical study: Anticoagulation can be started early after an ischemic stroke
by Swiss National Science Foundation Credit: CC0 Public Domain An international clinical study led by the Inselspital, Universitätsspital Bern, and the University of Bern has shown that anticoagulation (blood thinning) can be started earlier in people with a stroke and atrial fibrillation than previously recommended in the guidelines. Earlier treatment could reduce the risk of having another stroke...
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Transition to newer clot-busting drug improves patient outcomes, lowers cost in treating ischemic stroke
UNIVERSITY OF TEXAS AT AUSTIN IMAGE: TENECTEPLASE WORKS FASTER, LEADS TO BETTER OUTCOMES & COSTS ABOUT $2500 LESS PER PATIENT, ACCORDING TO NEW DELL MED STUDY. CREDIT: DELL MEDICAL SCHOOL A newer-generation clot-busting drug called tenecteplase outperforms the traditional treatment for ischemic strokes in several key areas, including better health outcomes and lower costs, according...
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Transition to newer clot-busting drug improves patient outcomes, lowers cost in treating ischemic stroke
by University of Texas at Austin Tenecteplase works faster, leads to better outcomes & costs about $2500 less per patient, according to new Dell Med study. Credit: Dell Medical School A newer-generation clot-busting drug called tenecteplase outperforms the traditional treatment for ischemic strokes in several key areas, including better health outcomes and lower costs, according...
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