by Vanderbilt University Medical Center Tet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-02854-6A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized...
by American Society of Nephrology Acute kidney injury (AKI), an abrupt decline in kidney function, often arises after major surgeries. A recent analysis indicates that taking certain reflux and ulcer medications that reduce stomach acid may put patients at an elevated risk of developing AKI following cardiac surgery. The findings will be presented online at...
by Children’s Hospital of Philadelphia Credit: CC0 Public Domain Researchers from a consortium of hospitals including Children’s Hospital of Philadelphia (CHOP) have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more...
Hiroko Sonoda, Byung Rho Lee, Ki-Hoon Park, Deepak Nihalani, Je-Hyun Yoon, Masahiro Ikeda& Sang-Ho Kwon Abstract Because exosomes have gained attention as a source of biomarkers, we investigated if miRNAs in exosomes (exo-miRs) can report the disease progression of organ injury. Using rat renal ischemia-reperfusion injury (IRI) as a model of acute kidney injury (AKI),...
Acute kidney injury, an often fatal condition without a specific treatment, affects up to 10 percent of all hospitalized adults in the United States and 30-40 percent in low-income countries. The condition causes a build-up of waste products in the blood and an imbalance of fluids throughout the body. Acute kidney injury can occur from...
