Peer-Reviewed Publication Centro Nacional de Investigaciones Oncológicas (CNIO) FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail image: Nabil Djouder and Mar Rigual, at their CNIO labview more Credit: CNIO The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, regeneration, which allows it to replace liver cells damaged by the very toxins that...
Tag: <span>liver regeneration</span>
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Researchers identify Lhx2 as key gene in hepatic stellate cells regulating liver regeneration and fibrosis
by Li Yali, Chinese Academy of Sciences Hepatic stellate cells play an important role in regeneration and fibrosis after liver injury, but the target genes that simultaneously regulate both processes in hepatic stellate cells are not yet clear. Credit: Prof. Wang’s team A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as...
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Drug can spur liver regeneration in Alagille syndrome
by Sanford Burnham Prebys Medical Discovery Institute Duc Dong, Ph.D. Credit: Sanford Burnham Prebys Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, published in the Proceedings of the...
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Tissue model reveals key players in liver regeneration
By tracing the steps of liver regrowth, MIT engineers hope to harness the liver’s regenerative abilities to help treat chronic disease. The human liver has amazing regeneration capabilities: Even if up to 70 percent of it is removed, the remaining tissue can regrow a full-sized liver within months. Caption:By tracing the steps of liver regrowth, MIT...
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Researchers identify cell type that regulates liver regeneration with touch
by Wellcome Trust A section of liver tissue, showing mesenchymal cells (in pink) contacting and wrapping around the liver ductal cells (also known as cholangiocytes, in yellow and blue) during the final stages of ductal-driven liver regeneration. All cell nuclei are visible in blue. Mesenchymal cells, with long cell protrusions, reminded the paper authors of octopuses....
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Study introduces mRNA-LNP as a safe therapeutic intervention for liver regeneration
by Boston University School of Medicine Credit: CC0 Public Domain When severely or chronically injured, the liver loses its ability to regenerate. A new study led by researchers at the Center for Regenerative Medicine at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) now describes a safe new potential therapeutic tool for the recovery of...
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New regulator for liver regeneration
The liver (orange) is the body’s detoxification centre and can regenerate completely after injury. By performing large-scale proteomics analysis of liver proteins, ETH researchers have discovered a protein that is essential for liver regeneration. They have also figured out the mechanism of the protein’s function. The liver is a wonderful thing: it’s the only...