Melanoma in skin biopsy with H&E stain — this case may represent superficial spreading melanoma. Researchers say a combination of new treatments can stop the world’s deadliest form of skin cancer—melanoma—in its tracks and halt its spread to other organs. Results from two international drug trials conducted by the Sydney-based Melanoma Institute Australia have proved successful...
Tag: <span>MELANOMA</span>
Post
Breaking the genetic resistance of lung cancer and melanoma
Researchers from Monash University and the Memorial Sloan Kettering Cancer Center (MSKCC, New York) have discovered why some cancers – particularly lung cancer and melanoma – are able to quickly develop deadly resistance to targeted therapies. Dr Luciano Martelotto, from the Monash University Faculty of Medicine, and his collaborators Dr Piro Lito and Yaohua Xue...
Post
People with Parkinson’s should be monitored for melanoma, study finds
People with the movement disorder Parkinson’s disease have a much higher risk of the skin cancer melanoma, and vice versa, a Mayo Clinic study finds. While further research is needed into the connection, physicians treating one disease should be vigilant for signs of the other and counsel those patients about risk, the authors say. The...
Post
Delaying lymph node biopsy after melanoma diagnosis does not affect survival rates
Postponing lymph node biopsy more than 30 days after melanoma diagnosis doesn’t adversely impact long-term clinical outcomes, according to new study findings published online as an “article in press” on the Journal of the American College of Surgeons website ahead of print publication. Every year, about 87,000 people are diagnosed with melanoma, according to the American Cancer Society....
Post
Study: Common surgical treatment for melanoma does not improve patients’ overall survival
Melanoma in skin biopsy with H&E stain — this case may represent superficial spreading melanoma. Patients who receive the standard surgical treatment for melanoma that has spread to one or more key lymph nodes do not live longer, a major new study shows. The study, published today in The New England Journal of Medicine, found...
Post
New immunotherapy combination shows promise for patients with advanced melanoma
Treatment with a combination of ipilimumab (Yervoy) and Coxsackievirus A21 (CVA21; Cavatak) led to durable responses in a number of patients with advanced melanoma, including some whose melanoma had progressed despite prior treatment with an immune checkpoint inhibitor, and fewer than anticipated adverse events, according to results from a phase Ib clinical trial presented here...
Post
Absent tumor-suppressors allow melanoma to thwart immunotherapy
Researchers identified a set of genetic changes that predict whether melanoma patients will respond to checkpoint inhibitor therapies. It’s what’s missing in the tumor genome, not what’s mutated, that thwarts treatment of metastatic melanoma with immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in Science Translational Medicine. Whole...
Post
Anti-aging gene identified as a promising therapeutic target for older melanoma patients
Pharmacologic activation of anti-aging gene with anti-diabetic drug could be used as adjuvant therapy for older melanoma patients who have developed resistance to targeted therapy PHILADELPHIA — (Feb. 23, 2017) — Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging...
Post
Patient self checks are critical to avoid potentially deadly melanoma recurrence
New study finds that recurrent melanomas are more likely to be found by patients as opposed to imaging Recurrences of early stage (stage II) melanoma are more often detected by patients and their physicians than by routine imaging tests, according to study results published online as an “article in press” on the Journal of the American...
Post
PROMISING NEW DRUG STOPS SPREAD OF MELANOMA BY 90 PERCENT
Michigan State University researchers have discovered that a chemical compound, and potential new drug, reduces the spread of melanoma cells by up to 90 percent. The man-made, small-molecule drug compound goes after a gene’s ability to produce RNA molecules and certain proteins in melanoma tumors. This gene activity, or transcription process, causes the disease to...