by Delthia Ricks , Medical Xpress Transcriptomic and TCR-based characterization of the CD8+ T cell populations from the PBMCs of the MS TWIN STUDY. Credit: Science Immunology (2024). DOI: 10.1126/sciimmunol.adj8094 Few autoimmune disorders are more challenging for patients than multiple sclerosis, a progressive condition that can affect vision, impair the ability to walk, cause extreme bouts of...
Tag: <span>multiple sclerosis (MS)</span>
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Multiple sclerosis trial suggests medication and cognitive behavioral therapy can reduce fatigue
Credit: Liza Summer from Pexels In a study of commonly used treatments for people with multiple sclerosis, both medical and behavioral interventions, and a combination of the two, resulted in meaningful improvements in fatigue, a University of Michigan-led study finds. The randomized clinical trial compared the effectiveness of modafinil, a wake-promoting medication used to treat sleepiness in...
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Multiple sclerosis: early warnings in the immune system
LMU researchers demonstrate that certain immune cells already play an important role in the early stages of multiple sclerosis. Multiple sclerosis (MS) is a chronic inflammatory disease in which the immune system attacks the central nervous system. This impairs the transmission of signals between the brain and body and can lead to deficits in vision,...
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Experimental Probiotic Uses Microbes to Treat Multiple Sclerosis in Mice
By DAVID NIELD An illustration of bacteria. (Artur Plawgo/Science Photo Library) Our immune system is made up of multiple smart defenses built into our bodies – but if those defenses go haywire, it can lead to diseases such as multiple sclerosis (MS). Scientists may have found a new way to control potentially dangerous autoimmune responses. A team from...
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Medicare patients with multiple sclerosis bear the burden of rising drug prices
by University of Pittsburgh Over the course of a decade, out-of-pocket costs for multiple sclerosis drugs rose more than sevenfold for Medicare Part D beneficiaries, according to a JAMA Neurology study published today by researchers at the University of Pittsburgh. Using Medicare claims data from 2006-2016, the researchers looked at trends in multiple sclerosis drug...
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How can exercise help with MS?
By Jamie EskeReviewed by Nancy Hammond, MD Benefits Aerobic exercises Progressive strength training Yoga Tai chi Water sports Balance exercises Safety Summary Exercise has a range of benefits for people with multiple sclerosis. It can, for example, help improve strength and mobility and boost mental well-being. In previous years, doctors recommended that people with multiple sclerosis (MS) avoid...
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Study finds red meat as part of a healthy diet linked to reduced risk of multiple sclerosis
People who consume unprocessed red meat as part of a healthy Mediterranean diet may reduce their risk of multiple sclerosis (MS), new research led by Curtin University and The Australian National University has found. The research, published in The Journal of Nutrition, examined data from 840 Australians who took part in the Ausimmune Study to determine whether there was a...
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Long-term benefits from intensive therapy in early stages of MS
New findings by researchers at Cardiff University suggest that intensive therapy during the early stages of multiple sclerosis (MS) leads to better long-term outcomes for patients, despite it often being viewed as a riskier option than other first line treatments. Dr Emma Tallantyre, from Cardiff University’s Division of Psychological Medicine and Clinical Neurosciences, said: “Over the last 10-20 years we have seen huge...
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Researchers identify how metabolites target brain-homing immune cells to treat MS
NEW YORK, February 28, 2019 – Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers. Now, a newly published paper featured on the March cover of the journal Brain adds significantly to this work by detailing how metabolites can be...
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Regulating the MS-causing properties of Th17 cells
Th17-cell differentiation. Satb1 is dispensable for the differentiation of Th17 cells but plays a pivotal role in the effector functions of pathogenic Th17 cells. EurekAlert! An international study group led by researchers from Osaka University identifies a protein regulator responsible for inducing the pathogenic properties of Th17 cells, leading to multiple sclerosis and other inflammatory...