Posted Today Penn Engineers have modified lipid nanoparticles (LNPs) — the revolutionary technology behind the COVID-19 mRNA vaccines — to not only cross the blood-brain barrier (BBB) but also to target specific types of cells, including neurons. This breakthrough marks a significant step toward potential next-generation treatments for neurological diseases like Alzheimer’s and Parkinson’s. Emily Han, a doctoral...
Tag: <span>nanoparticle delivered RNA</span>
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Nanoparticle-delivered RNA reduces neuroinflammation in lab tests
In mice and human cell cultures, MIT researchers showed that novel nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s disease Peer-Reviewed Publication PICOWER INSTITUTE AT MIT A FIGURE FROM THE PAPER SHOWS THAT AN SIRNA DELIVERED BY A LIPID NANOPARTICLE WAS ABLE TO REDUCE EXPRESSION OF THE...