by Salk Institute Human astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain. The other half—roughly 85 billion cells—are non-neuronal cells called glia. The most common...
The study defines a new neuroscientific paradigm (synergistic model), which allows to better understand the complexity of the interactions between brain, body and environment and paves the way to being able to integrate different levels of brain diseases.Peer-Reviewed Publication UNIVERSITAT POMPEU FABRA – BARCELONA SYNERGETIC FRAMEWORK.CREDIT: TRENDS IN COGNITIVE SCIENCES How does our brain interact...
by University of Zurich Progressive degeneration in a neuronal network: blue represents healthy neurons, while orange and red represent the protein NPTX2. Yellow shows the toxic aggregation of the protein TDP-43. Credit: Niklas BargendaScientists at the University of Zurich have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration. Their...
by Massachusetts Institute of Technology Credit: CC0 Public DomainAny drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s not known which of those transporters they use to exit the digestive tract. Identifying...
Hebrew University of Jerusalem Hebrew University study proposes a new model suggesting that disrupted RNA editing within pancreatic beta cells might initiate an inflammatory response akin to early-stage type 1 diabetes. This new perspective challenges the long-held belief of viral involvement, offering potential implications for treatments and cures. A recent study by researchers at the...
ALICE FERNG Arriving in two boxes reminiscent of Apple product packaging – one for the chest piece (the part that contacts the body), and another for the detachable earpiece (tubes + ear tips) – the CORE 500 is clearly an upgrade from the Eko DUOstethoscope. Similar to its predecessor, the CORE 500 can be used...
by Boston University School of Medicine In vitro differentiation of iPSCs toward the lung mesenchyme lineage through a mesodermal progenitor. a Schematic of the Tbx4 lung enhancer reporter/tracer (LER) line, and image of an E10 embryo (dox from E6.5 to E10). Scale bar = 0.5 mm. Created with BioRender.com. b Directed differentiation of iPSCs into lung mesenchyme through a mesodermal progenitor. cSFDM = complete serum-free differentiation medium,...
MASSACHUSETTS INSTITUTE OF TECHNOLOGY IMAGE: BY APPLYING A LANGUAGE MODEL TO PROTEIN-DRUG INTERACTIONS, RESEARCHERS CAN QUICKLY SCREEN LARGE LIBRARIES OF POTENTIAL DRUG COMPOUNDS. CREDIT: ISTOCK CAMBRIDGE, MA — Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each...
by University of Tsukuba Credit: Olimpik/Shutterstock Even seemingly simple movements are very complex to perform, and the way we learn how to perform new movements remains unclear. Researchers from Japan have recently proposed a new model of motor learning that combines a number of different theories. A study published this month in Neural Networks revealed that their...
By CARLA K. JOHNSON Joyce Ares had just turned 74 and was feeling fine when she agreed to give a blood sample for research. So she was surprised when the screening test came back positive for signs of cancer. After a repeat blood test, a PET scan and a needle biopsy, she was diagnosed with...
