Megan Brooks January 31, 2025 15223 The US Food and Drug Administration (FDA) has approved suzetrigine 50 mg tablets (Journavx, Vertex Pharmaceuticals), a first-in-class nonopioid analgesic for treatment of adults with moderate-to-severe acute pain. Suzetrigine selectively inhibits the NaV1.8 pain-signaling pathway in the peripheral nervous system, a validated target for peripheral pain management. Because suzetrigine...
Tag: <span>NSAIDs</span>
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Who Should Not Take NSAIDs? 9 People Who Should Avoid These Pain Relievers
Written by Christina Aungst, PharmD | Reviewed by Austin Ulrich, PharmD, BCACP Published on August 15, 2024print_outlinedemail_outlined Key takeaways: Table of contents Kidney disease Heart disease Pregnancy Stomach ulcers Older adults Diabetes Inflammatory bowel disease Blood thinners Other interacting meds FAQs Bottom line References KTStock/iStock via Getty Images Plus Nonsteroidal anti-inflammatory drugs (NSAIDs) are a very well-known class...
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Combining NSAIDs and TNFi may reduce radiographic progression in ankylosing spondylitis
June 14, 2018, European League Against Rheumatism The results of a cohort study presented at the Annual European Congress of Rheumatology (EULAR 2018) showed that, in patients with ankylosing spondylitis (AS) taking tumour necrosis factor (TNF) inhibitors, the addition of non-steroidal anti-inflammatory drugs (NSAIDs) was associated with significantly less radiographic progression in a dose-related manner at...
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The drugs don't work, say back pain researchers
Commonly used non-steroidal anti-inflammatory drugs, such as ibuprofen, used to treat back pain provide little benefit, but cause side effects, according to new research from The George Institute for Global Health. The findings of the systematic review, published in the Annals of the Rheumatic Diseases, reveal only one in six patients treated with the pills, also...