Tag: <span>oestrogen</span>

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Abundance of key immune cells may be influenced by estrogen and XX chromosomes

by University College London Credit: Journal of Experimental Medicine (2025). DOI: 10.1084/jem.20241253 Women have a higher proportion of key immune cells between puberty and menopause, which may be linked to the sex hormone estrogen and explain why they are less susceptible to certain infectious diseases than men, according to a new study led by researchers at UCL. The...

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Discovery of estrogen receptor ‘switches’ may aid breast cancer treatment

by Case Western Reserve University Hydrophobic clustering in ER-NTD. Credit: Nature (2025). DOI: 10.1038/s41586-024-08400-1 Researchers at Case Western Reserve University School of Medicine have discovered how specific protein regions contribute to breast cancer. Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of...

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Preclinical study finds surges in estrogen promote binge drinking in females

Peer-Reviewed Publication Weill Cornell Medicine The hormone estrogen regulates binge drinking in females, causing them to “pregame” – consume large quantities of alcohol in the first 30 minutes after it’s offered, according to a preclinical study led by scientists at Weill Cornell Medicine. The study establishes–for what is thought to be the first time–that circulating...

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Improving breast cancer treatment

Oestrogen receptive positive breast cancer can be treated by drugs, such as fulvestrant, that interfere with the action of oestrogen. Although these drugs are often effective for a while, the cancer can frequently become resistant and the drugs stop working. In the trial, researchers investigated whether they could reverse or delay resistance to hormone therapy in post -menopausal women whose cancer had...