by Celia Luterbacher, Ecole Polytechnique Federale de Lausanne Demonstration of the easily injectable hydrogel flowbone. Credit: flowbone/EPFL LBO Osteoporosis is a disease in which bone resorbs faster than it is formed, gradually weakening its structure over time and leading to fractures. Although the condition is well recognized, Dominique Pioletti, head of the Laboratory of Biomechanical Orthopedics...
Tag: <span>Osteoporosis</span>
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A ‘Nagging Gap’: Screening Men for Osteoporosis
Lucy Hicks January 24, 2025 4182 Earlier this month, the US Preventive Services Task Force (USPSTF) released updated screening recommendations for osteoporosis. The task force reaffirmed their 2018 recommendations that all women aged 65 years or older and postmenopausal women younger than 65 years at increased risk for osteoporotic fracture should be screened. Notably, there...
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US Preventive Services Task Force recommends osteoporosis screening for women 65 years and older
by Elana Gotkine The U.S Preventive Services Task Force (USPSTF) recommends osteoporosis screening to prevent osteoporotic fractures for all women aged 65 years and older and for postmenopausal women aged younger than 65 years at increased risk. These findings form the basis of a final recommendation statement published online Jan. 14 in the Journal of the American Medical...
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Researchers find new biomarkers for osteoporosis diagnosis and treatment
by Hospital for Special Surgery Circulating osteoclast precursor cells decrease in patients with osteoporosis treated with denosumab. Credit: JCI Insight (2024). DOI: 10.1172/jci.insight.178977 Researchers at Hospital for Special Surgery (HSS) have pinpointed a cellular target that could enhance the way osteoporosis and other metabolic bone diseases are diagnosed and treated. The findings, published recently in JCI Insight, reveal that circulating...
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Nucleic acid drug iSN40 shows promise for osteoporosis treatment
by Shinshu University In a new study, researchers from Japan reveal that iSN40 suppresses osteoclast differentiation and bone matrix resorption, offering a potential therapeutic approach for osteoporosis by restoring the balance between bone formation and resorption. Credit: Dr. Tomohide Takaya, Shinshu University, Japan Osteoporosis, characterized by an imbalance in bone remodeling, is a growing health concern...
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Genetic variants in melatonin receptor linked to idiopathic osteoporosis
by Justin Jackson , Medical Xpress Credit: cottonbro studio from Pexels Columbia University Medical Center researchers have identified specific variants in a melatonin receptor gene that impair bone turnover, leading to significant reductions in bone density and increased risk of fractures, particularly in Ashkenazi Jewish individuals. Osteoporosis is a common bone disorder characterized by low...
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Protein blocking bone development could hold clues for future osteoporosis treatment
Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation. In their paper published in Communications Biology 11 October 2024, a team of researchers led by Dr. Amy Naylor and Professor Roy Bicknell along with their team including Dr. Georgiana Neag...
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New gene linked to osteoporosis identified
JULY 1, 2024 by Osaka University Molecular mechanism of senescence induced by osteoblast MEN1 deficiency SASP: senescence-associated secretory phenotype. Credit: Aging Cell (2024). DOI: 10.1111/acel.14254Osteoporosis—weakening of the bones with age—affects millions worldwide, and this figure is increasing annually as the global population ages. It is associated with the aging, or “senescence,” of bone cells, but...
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USPSTF recommends osteoporosis screening for women aged 65 years and older
JUNE 11, 2024 by Elana Gotkine The U.S. Preventive Services Task Force (USPSTF) recommends screening for osteoporosis for women aged 65 years and older and for postmenopausal women younger than 65 years with one or more risk factors. These recommendations form the basis of a draft recommendation statement published online June 11. Researchers reviewed the...
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HKU scientists unveil significant discovery with potential impact on obesity and osteoporosis treatments
THE UNIVERSITY OF HONG KONG SECRETIN SIGNALING IN THE VENTROMEDIAL HYPOTHALAMUS REGULATES SKELETAL AND METABOLIC HOMEOSTASIS. IMAGE ADAPTED FROM RESPECTIVE PAPER IN NATURE COMMUNICATIONS (2024) view moreCREDIT: THE UNIVERSITY OF HONG KONG A team of researchers from The University of Hong Kong (HKU) has made a significant breakthrough in understanding how energy metabolism and bone...