by Levi Gadye, University of California, San Francisco Intrinsic reactivity and stability of G12Di-6 and 7. a, Stability in the presence of excess compounds (5 mM) bearing reactive functional groups. All data points represent individual biological replicates. Data are presented as mean ± SD (n = 2). b, Stability in 1X PBS at various pH. All data points represent individual biological...
Tag: <span>Pancreatic cancer</span>
Age-related changes in fibroblast cells promote pancreatic cancer growth and spread
by Johns Hopkins University School of Medicine Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainOlder people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns...
TEAM UNCOVERS A KEY ACTOR IN PANCREATIC CANCER’S SPREAD
POSTED BY ANDY FELL-UC DAVIS Researchers have identified a protein linked to metastasis in pancreatic cancer. Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed. Severe pancreatic cancer is associated with metastasis, and it is this spread of secondary tumors...
Vaccine targeting KRAS in pancreatic and colorectal cancer shows promise
Peer-Reviewed Publication MEMORIAL SLOAN KETTERING CANCER CENTER MEMORIAL SLOAN KETTERING CANCER CENTER MEDICAL ONCOLOGIST EILEEN O’REILLY HELPED LEAD A CLINICAL TRIAL INVESTIGATING A READY-MADE VACCINE AS A TREATMENT FOR PANCREATIC AND COLORECTAL CANCERS WITH CERTAIN KRAS MUTATIONS.CREDIT: MEMORIAL SLOAN KETTERING A new vaccine shows encouraging early results as a potential off-the-shelf treatment for certain patients...
New potential immunotherapies for pancreatic cancer
by Rush University Medical Center Neutralization of p402 and p40 increases levels of IFN-γ in pancreatic cancer cells. Immunohistochemical analysis at 60× magnification of PANC-1 (A) and BxPC-3 cells (B) treated with p40 homodimer or p40 monomer were labeled with IFN-γ (red). DAPI was used to stain the nuclei. Cells positive for IFN-γ were counted and...
Vaccine demonstrates potential in delaying relapse of KRAS-mutated pancreatic and colorectal cancers
by University of Texas M. D. Anderson Cancer Center Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA vaccine has shown potential to prevent relapse of KRAS-mutated pancreatic and colorectal cancers for patients who had previously undergone surgery, according to a Phase I trial led by researchers at The...
New approach to pancreatic cancer treatment expands therapeutic possibilities, shows promise for increased survival
by Virginia Commonwealth University Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer. Researchers from VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM)...
Study directly links high insulin levels to pancreatic cancer
by University of British Columbia Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer Institute A new study from researchers at the University of British Columbia’s Faculty of Medicine reveals a direct link between high insulin levels, common among patients with obesity and type 2 diabetes, and pancreatic cancer....
Licorice found to fight pancreatic cancer in lab studies
By Michael Franco August 16, 2023 Although stick-like in its appearance, licorice root is quite different from the popular candy store treat Depositphotos Typically thought of as a bendy black confection, the root form of licorice has long been used in traditional Chinese medicine to treat a range of conditions. Now, a new study shows...
Treatment potential of herbal extract compound isoliquiritigenin for pancreatic cancer
by Hong Kong Baptist University A research team led by Dr Joshua Ko Ka-shun, Associate Professor, Teaching and Research Division of the School of Chinese Medicine at HKBU, found that isoliquiritigenin, a herbal extract compound of the Chinese herbal medicine licorice, can inhibit pancreatic cancer progression. Credit: Hong Kong Baptist University Research led by scientists of...