by Tracey Peake, North Carolina State University Credit: Unsplash/CC0 Public DomainResearchers from North Carolina State University have pinpointed a particular peptide’s role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition. Atopic dermatitis (AD) is a skin condition characterized by itching, irritated and thickened skin at the site...
FEBRUARY 15TH, 2023 CONN HASTINGS MATERIALS, SURGERY Researchers at Rice University have developed a bioprinting method that uses self-assembling peptides as a bioink. The technique involves using “multidomain peptides” that are hydrophobic at one end and hydrophilic at the other. When the peptides encounter water, they flip over each other to create hydrophobic sandwich structures that stack...
While biologists and chemists race to develop new antibiotics to combat constantly mutating bacteria, predicted to lead to 10 million deaths by 2050, engineers are approaching the problem through a different lens: finding naturally occurring antibiotics in the human genome. The billions of base pairs in the genome are essentially one long string of code...
by Children’s Hospital Boston This schematic shows the peptides P1 and P2 with hydrophobic modifications that enable them to self-assemble into nanostructures that bind to tetrodotoxin (TTX). Credit: Tianjiao Ji, PhD, Kohane lab in Nature Biomedical Engineering, Sept. 13, 2021. Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local...
Share on Pinterest New research suggests a peptide-based nasal spray could inactivate SARS-CoV-2 before it infects cells. Karl Tapales/Getty Images Previous research has shown SARS-CoV-2 causes an infection in a person by entering the body and binding its spike proteins to ACE2 receptors on a cell’s surface. Researchers have designed peptides that resemble the ACE2 receptors targeted by the viral spike proteins....
By Dr. Liji Thomas, MD Jan 15 2021 As the world continues to struggle with the coronavirus disease 2019 (COVID-19) pandemic, researchers are busy searching for pharmaceuticals that can effectively counteract the pathogen. This causative agent, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), infects through engagement via its spike protein with the host cell, attaching to the angiotensin-converting...
UNIVERSITAT AUTONOMA DE BARCELONA IMAGE: SCHEMATIC REPRESENTATION OF HOW THE CONJUGATE OF THE PEPTIDE + THE DRUG MANAGES TO ENTER INSIDE THE CELL OF THE PARASITE TO ELIMINATE IT (UAB) Leishmaniasis is caused by the protozoan Leishmania parasites which are transmitted by the bite of an infected sandfly. Although in rich countries this disease mainly...
Designer peptide could become effective in reducing damage caused by COVID-19 infections UNIVERSITY OF TORONTO – FACULTY OF DENTISTRY TORONTO, ON (June 30, 2020) — A collaboration between the University of Toronto’s Faculty of Dentistry and the National Jewish Health in Denver — the top-ranked respiratory research hospital in the U.S. — has yielded a...
Research demonstrates how Rensselaer-made peptides can bind to cells and potentially block viruses Designer peptides show potential for blocking viruses, e TROY, N.Y. — Chemically engineered peptides, designed and developed by a team of researchers at Rensselaer Polytechnic Institute, could prove valuable in the battle against some of the most persistent human health challenges. The...
Research demonstrates how Rensselaer-made peptides can bind to cells and potentially block viruses RENSSELAER POLYTECHNIC INSTITUTE Designer peptides show potential for blocking viruses, e TROY, N.Y. — Chemically engineered peptides, designed and developed by a team of researchers at Rensselaer Polytechnic Institute, could prove valuable in the battle against some of the most persistent human...
