EXPERIMENTAL STRATEGY. MASUKI ET AL. COMPR PHYSIOL 10: 1207-1240, 2020. view more CREDIT: COPYRIGHT © 2020 AMERICAN PHYSIOLOGICAL SOCIETY A common notion is to walk 10,000 steps a day to improve ones’ physical fitness, so pedometers have been a popular wearable health device from before the days of fitness trackers and smartphones. However, simply walking...
Tag: <span>PHYSIOLOGICAL</span>
From virtual to reality! Virtual training improves physical and cognitive functions
THE VIRTUAL BODY AS EXPERIENCED BY THE USER view more CREDIT: TOHOKU UNIVERSITY Researchers at the Smart-Aging Research Center (IDAC) at Tohoku University have developed an innovative training protocol that, utilizing immersive virtual reality (IVR), leads to real physical and cognitive benefits. We all know that physical exercise is crucial for overall well-being and helps...
Ultraviolet B exposure expands proenkephalin+ regulatory T cells with a healing function
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function NAGOYA CITY UNIVERSITY UVB IRRADIATION INDUCES PROLIFERATION AND ACTIVATION OF SKIN TREG CELLS. UVB-EXPANDED SKIN TREG (UVB-SKIN TREG) CELLS PROMOTE WOUND HEALING BY PRODUCING ENKEPHALIN AND AMPHIREGULIN(AREG), WHICH ENHANCE KERATINOCYTE GROWTH/PROLIFERATION TO REPAIR… view more CREDIT: DEPARTMENT IMMUNOLOGY, NAGOYA...
Newly discovered ‘support system’ for axons suggests a novel therapeutic target for neurodegenerative diseases
by Ellen Goldbaum, University at Buffalo This image shows axons in vitro 24 hours after injury. The presence of Schwann cells (nuclei in cyan) helped maintain the integrity of axons (in magenta and yellow). Credit: Elisabetta Babetto, HJKRI Axons are long, finger-like projections of neurons that transmit critical signals throughout the nervous system. But because...
Scientist unveils a 3-D printed device to excite nerves
by Jim Barlow, University of Oregon A tiny, thin-film electrode with a 3-D-printed housing has been implanted in the peripheral nervous system of songbirds, where it successfully recorded electrical impulses that drive vocalizations. The research is seen as an advance in the emerging field of bioelectronic medicine and eventually could lead to a new treatment...
Stomach SIDT1 mediates dietary microRNA absorption: ending of the 10-year debate
NANJING UNIVERSITY SCHOOL OF LIFE SCIENCES In a new study published in Cell Research, Chen-Yu Zhang’s group at Nanjing University School of Life Sciences, China, reports that SIDT1 in the mammalian stomach mediates host uptake of dietary and orally administered microRNAs (miRNAs), thus exerting biological functions in the host. In previous studies, Chen-Yu Zhang’s group...
Research exposes new vulnerability for SARS-CoV-2
Electrostatic interactions enhance the spike protein’s bond to host cells NORTHWESTERN UNIVERSITY A COMPUTER MODEL SHOWING THE POLYBASIC CLEAVAGE SITES, LOCATED ON THE NOVEL CORONAVIRUS’ PROTEIN SPIKE. view more CREDIT: NORTHWESTERN UNIVERSITY EVANSTON, Ill. — Northwestern University researchers have uncovered a new vulnerability in the novel coronavirus’ infamous spike protein — illuminating a relatively simple,...
The CNIO pave the way for a future gene therapy to reverse pulmonary fibrosis associated with ageing
CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) DEVELOPMENT OF THE INITIAL STAGES OF PULMONARY FIBROSIS ASSOCIATED WITH AGEING IN NON-TREATED MICE (LEFT), THAT CAN BE PREVENTED IN MICE TREATED WITH THE TELOMERASE GENE THERAPY (RIGHT). view more CREDIT: CNIO Idiopathic pulmonary fibrosis is a potentially lethal disease for which there is currently no cure and that...
ASTHMA DOESN’T SEEM TO BOOST COVID-19 RISK
Asthma does not seem to increase the risk of a person contracting COVID-19 or influence its severity, according to new research. Researchers say further study is needed but those with the chronic respiratory disease don’t appear to be at a higher risk of getting extremely ill or dying from coronavirus. “Older age and conditions such...
Osmotic stress identified as stimulator of cellular waste disposal
IMAGE OF MOUSE ASTROCYTES SHOWING THE ACTIN CYTOSKELETON (RED) AND LYSOSOMES (GREEN) view more CREDIT: TANIA LOPEZ-HERNANDEZ Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system. This recycling process...
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