by Medical University of Vienna Credit: Immunity (2025). DOI: 10.1016/j.immuni.2025.02.011 Psoriasis is one of the most common chronic inflammatory skin diseases, affecting about 250,000 people in Austria. While previous treatment approaches have mainly focused on inhibiting pro-inflammatory immune cells, a study led by MedUni Vienna shows that it is possible to restore the function of certain anti-inflammatory immune...
Tag: <span>Psoriasis</span>
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Real-world study shows effectiveness of ixekizumab for psoriasis
by Elana Gotkine For patients with moderate-to-severe plaque psoriasis, ixekizumab is effective and safe, with induction therapy enhancing initial response, according to a study published online in the Journal of Clinical Medicine. ADVERTISING Ricardo Ruiz-Villaverde, M.D., Ph.D., from Hospital Universitario San Cecilio in Granada, Spain, and colleagues conducted a multicenter, observational study involving 183 patients with moderate-to-severe plaque psoriasis to...
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Light-activated drug shows promise for fighting psoriasis
by University of Barcelona Credit: Journal of the American Chemical Society (2024). DOI: 10.1021/jacs.4c13558 Psoriasis is a chronic skin disease that manifests itself mainly with skin symptoms (dryness, itching, scaly skin, abnormal patches and plaques). It affects about 2% of the population and is mediated by an altered immune system response that triggers the proliferation of skin cells....
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Key protein that intensifies psoriasis identified
by Case Western Reserve University c-Rel deficiency protects mice from TLR7-induced psoriasiform skin pathology but not from systemic inflammation. Psoriasis, a painful and uncomfortable inflammatory skin condition that affects millions worldwide, flares up from the activity of disease- and infection-protecting immune cells. In a new study, researchers at Case Western Reserve University School of Medicine have...
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Inflammation may explain stomach problems in psoriasis sufferers
Peer-Reviewed Publication Uppsala University FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail image: Docent Maria Lampinen, researcher at the Department of Pharmacy, Uppsala University, Sweden. view more Credit: Mikael Wallerstedt People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for ‘leaky gut’, according to new research at Uppsala University. These changes in the gut could...
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Ultraprocessed foods might help trigger psoriasis
by Ernie Mundell Ultraprocessed foods have been linked to a myriad of health issues, and a new study suggests that the autoimmune skin disease psoriasis might be added to that list. “Results of this study showed an association between high ultraprocessed food intake and active psoriasis status,” concluded a team led by Dr. Emilie Sbidian,...
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Increased psoriasis risk found in cancer patients treated with immune checkpoint inhibitors
by Justin Jackson , Medical Xpress Credit: Estzer Miller on Pixabay Researchers from the National Defense Medical Center in Taiwan have identified an increased risk of psoriasis in patients with cancer undergoing immune checkpoint inhibitor (ICI) treatments, with implications for other immune-related adverse events. Over the past decade, ICIs have become an increasingly important part...
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Psoriasis patients can get clearer skin with at-home treatment instead of at doctors’ offices, study suggests
by Alex Gardner, Perelman School of Medicine at the University of Pennsylvania Credit: Estzer Miller on Pixabay For decades, people with psoriasis have been treated in clinics with narrowband ultraviolet B phototherapy, or light therapy, to reduce sores, scales, and inflammation. Now, new research from the Perelman School of Medicine at the University of Pennsylvania shows...
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How Do Tapinarof and Roflumilast Creams Fit Into Psoriasis Treatment?
HUNTINGTON BEACH, Calif. — The US Food and Drug Administration (FDA) approvals of tapinarof 1% cream and roflumilast 0.3% cream as treatment options for patients with plaque psoriasis came more than 1 year after the American Academy of Dermatology/National Psoriasis Foundation Guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine...
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Comorbidities Associated With Psoriasis: 5 Things to Know
Psoriasis is an immune-mediated chronic inflammatory skin disease that affects approximately 2%-4% of adults in Western countries. Over the past decade, discovery of the pathogenic pathways in psoriasis has led to a greater understanding of the role psoriasis plays in systemic inflammation and associated comorbidities. Several recent studies have shown that patients with psoriasis have higher rates of comorbid...