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Better health diagnostics through genetically engineered embedded sentinel cells

by Justin Jackson , Phys.org Blue-sky opportunities for monitoring and altering disease progression. Credit: Nature Reviews Genetics (2024). DOI: 10.1038/s41576-024-00788-w Cells can now be genetically programmed to record their histories within their genomes, a development that could revolutionize the study of developmental and disease processes, according to a collaborative work by researchers from multiple institutions including the...

Immune system ‘sentinel’ cells key to maintaining and regulating response to immunotherapy
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Immune system ‘sentinel’ cells key to maintaining and regulating response to immunotherapy

by University of Melbourne A part of the spleen during chronic viral infection. Dendritic cells are green, killer T cells are red, B cells are blue and stromal cells are magenta. Credit: Würzburg Institute of Systems Immunology, Max-Planck Research Group. The presence of dendritic cells, so-called ‘sentinel’ immune cells, is vital to maintain and regulate...