Tag: <span>thalassemia</span>

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Enzyme identified as possible novel drug target for sickle cell disease, Thalassemia

July 19, 2018, Children’s Hospital of Philadelphia Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease (SCD). Experiments in cultured human cells reveal that blocking the protein reduces the characteristic sickling that distorts the...

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Major breakthrough in the manufacture of red blood cells

Researchers have generated the first immortalised cell lines which allow more efficient manufacture of red blood cells. The team, from the University of Bristol and NHS Blood and Transplant, were able to manufacture red blood cells in a more efficient scale than was previously possible. The results, published in Nature Communications, could, if successfully tested in...