Tag: <span>Transcription Factor</span>

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Transcription factor binding sites may help explain underlying causes of many diseases

by Melissa Rohman, Northwestern University Expression patterns of several worm transcription factors showing the diversity of expression. Shown are merged green fluorescent protein and DIC images. Credit: Bridget Lear, PhD.   A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in Genome...

Surprising Behavior of Transcription Factors Challenges Theories of Gene Regulation
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Surprising Behavior of Transcription Factors Challenges Theories of Gene Regulation

How cells develop and the diseases that arise when development goes wrong have been a decades-long research focus in the laboratory of Distinguished Professor of Biology Ellen Rothenberg. In particular, the lab studies the development of immune cells known as T cells, which act as “intelligence agents”—they circulate throughout the body, detect threats, and determine what kind of...