by University of Cincinnati Micrograph showing cortical pseudolaminar necrosis, a finding seen in strokes on medical imaging and at autopsy. H&E-LFB stain. Credit: Nephron/Wikipedia A new groundbreaking study from the University of Cincinnati shows promise that a new drug may help repair damage caused by strokes. Researchers from UC and Case Western Reserve University published...
New needle-free nasal vaccine shows promise for COVID-19
by American Society for Microbiology Credit: CC0 Public Domain New research shows that a needle-free mucosal bacteriophage (phage) T4-based COVID-19 vaccine is effective against SARS-CoV-2 infection. The findings were published in mBio, an open access journal of the American Society for Microbiology. In recent years, the Food and Drug Administration authorized mRNA- and adenovirus-based SARS-CoV-2 vaccines....
Scientists create nanobody that can punch through tough brain cells and potentially treat Parkinson’s disease
by Johns Hopkins University School of Medicine The structure of alpha-synuclein clumps (on the left) was disrupted by the nanobody PFFNB2 (as shown on the right). Credit: Xiaobo Mao Proteins called antibodies help the immune system find and attack foreign pathogens. Mini versions of antibodies, called nanobodies—natural compounds in the blood of animals such as...
Cytisine may prove a safe and effective smoking cessation therapy
by International Association for the Study of Lung Cancer Credit: CC0 Public Domain Research published in the Journal of Thoracic Oncology shows cytisine may be a safe and effective smoking cessation therapy in lung cancer screening volunteers. Cytisine is a plant-based alkaloid that is extracted from Cytisus laburnum and is a selective partial agonist nicotinic acetylcholine...
New rabies vaccine candidate demonstrates promising immune response and safety
by University of Oxford Credit: CC0 Public Domain Researchers from the University of Oxford have today reported new findings from a Phase 1 clinical trial studying the immune response and safety of their newly-developed single shot rabies vaccine, ChAdOx2 RabG—with promising results identified. The RAB001 trial was conducted at the University and is the first...
People with poor sleep behaviors may be at risk for fatty liver disease
by The Endocrine Society Credit: Pixabay/CC0 Public Domain People with sedentary lifestyles and unhealthy sleep behaviors could develop fatty liver disease, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Fatty liver disease is the leading chronic liver disease worldwide, affecting about a quarter of the adult population. This type...
Ketamine found to be unlikely to lead to addiction
by Bob Yirka, Medical Xpress 3D model of Ketamine. Credit: Wikipedia A team of researchers at the University of Geneva has found that ketamine is unlikely to be addictive to people who use it for extended periods of time. In their paper published in the journal Nature, the group describes their study of the impact of...
Researchers provide new framework for studying brain organization
by University of California, Los Angeles Credit: Pixabay/CC0 Public Domain UCLA researchers and colleagues at Emory University and other research centers have combined data simulation and experimental observation to bridge a gap between two major properties of large-scale organization of the human brain—stationary and traveling waves of activity. “Functional magnetic resonance imaging suggests the brain...
Researchers invent accurate rapid COVID-19 antibody level test
by City University of Hong Kong Dr Chen Ting-Hsuan, Associate Professor, Department of Biomedical Engineering, City University of Hong Kong, holding a microfluidic device. Credit: City University of Hong Kong Vaccines have become the most important weapon in the fight against the COVID-19 pandemic, but antibody levels after vaccination decay quickly over time. Therefore, an...
COVID vaccine patch fights variants better than needles
by University of Queensland A vaccine patch. Credit: The University of Queensland A needle-free vaccine patch could better fight COVID-19 variants, such as Omicron and Delta, than a traditional needle vaccine according to a University of Queensland study in mice. The research, conducted in partnership with Brisbane biotechnology company Vaxxas, tested the Hexapro SARS-CoV-2 spike vaccine using...