Category: <span>Inflammation</span>

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Study unveils a global dysregulation of dopamine in mice with chronic inflammatory pain
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Study unveils a global dysregulation of dopamine in mice with chronic inflammatory pain

by Ingrid Fadelli , Medical Xpress Microscopic image of the anterior cingulate cortex (ACC) used for the current experiment. The black lines are the stimulation electrodes that were used to evoke synaptic responses, while the white lines show the placement of the recording electrode that monitored the activity of the neurons. Image credit: Soroush Darvish-Ghane....

Calorie reduction lowers protein linked to the aging process
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Calorie reduction lowers protein linked to the aging process

by Yale University Credit: Pixabay/CC0 Public Domain Reduced calorie intake has been shown to improve health and lifespan in laboratory animals, and recent research shows these benefits may extend to humans as well. In a new study, Yale researchers show that moderate calorie restriction in people reduces the production of a protein called SPARC, which...

Potential long-term treatment for asthma found
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Potential long-term treatment for asthma found

by  Aston University Credit: Pixabay/CC0 Public Domain A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London. In tests in mice, the researchers were able to virtually eliminate asthmatic symptoms within two weeks and return their airways to near normal. Just under...

Down on Vitamin D? It could be the cause of chronic inflammation
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Down on Vitamin D? It could be the cause of chronic inflammation

by University of South Australia There’s a direct link between low levels of vitamin D and high levels of inflammation. Credit: Rebecca Wood Inflammation is an essential part of the body’s healing process. But when it persists, it can contribute to a wide range of complex diseases including type 2 diabetes, heart disease, and autoimmune...

‘Inside out’ signaling promotes tumor growth
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‘Inside out’ signaling promotes tumor growth

by Will Doss, Northwestern University Pharmacological inhibitor of MLCK MW01-022AZ suppressed tumor inflammation and growth. a Schematic of LLC lung tumor implantation in C57Bl6 mice and MW01-022AZ treatment. b–d Effect of MW01-022AZ on LLC b gross tumor morphology (n = tumors from 6 mice) c tumor volume (n = 9 mice and d tumor weight at endpoint (21 days)...

B vitamins can potentially be used to treat advanced non-alcoholic fatty liver disease
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B vitamins can potentially be used to treat advanced non-alcoholic fatty liver disease

by Federico Graciano, Duke-NUS Medical School Western-style diets, which are typically high in fructose intake, can lead to elevated serum and hepatic homocysteine levels in blood (a medical condition known as hyperhomocysteinemia), which the research team found to be directly proportional to the severity of non-alcoholic steatohepatitis (NASH) in people with non-alcoholic fatty liver disease...

Inflammation accelerates aging of the hematopoietic system
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Inflammation accelerates aging of the hematopoietic system

by German Cancer Research Center Credit: Unsplash/CC0 Public Domain In mice, inflammation in early to mid-life leads to a permanent decline in functional blood stem cells, according to a recent publication by scientists from the German Cancer Research Center (DKFZ) and the Stem Cell Institute HI-STEM. The ability of the blood stem cells to regenerate...

Stimulating the auricular vagus nerve has anti-inflammatory effects in severe Covid-19 cases
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Stimulating the auricular vagus nerve has anti-inflammatory effects in severe Covid-19 cases

VIENNA UNIVERSITY OF TECHNOLOGY IMAGE: FROM LEFT: EUGENIJUS KANIUSAS, BABAK DABIRI UND ANDREAS DICKINGER CREDIT: TU WIEN A system out of balance When a virus – such as SARS-CoV-2 – triggers an inflammatory response in the body, this information is transmitted to the brain via the sensory nervous system. The Vagus nerve, which extends from...

Scientists uncover new therapeutic target for treating colorectal tumors
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Scientists uncover new therapeutic target for treating colorectal tumors

TOKYO UNIVERSITY OF SCIENCE IMAGE: A NEW STUDY BY RESEARCHERS FROM JAPAN AND CHINA HAS REVEALED THAT INHIBITING DCIR, A C-TYPE LECTIN RECEPTOR PROTEIN RESPONSIBLE FOR MAINTAINING HOMEOSTASIS IN THE IMMUNE AND BONE SYSTEMS, REDUCES THE SEVERITY OF DSS COLITIS SYMPTOMS AND SUPPRESSES COLORECTAL TUMOR GROWTH. THESE FINDINGS COULD PAVE THE WAY FOR THERAPEUTIC STRATEGIES...