by Emory University Credit: Pixabay/CC0 Public Domain In a paper published recently in Pharmacological Reviews, Emory University School of Medicine researchers outlined the impact of inflammation on motivation as it relates to depression. The researchers propose that low grade inflammation affects brain chemicals and brain circuits that regulate motivation, ultimately leading to motivational deficits and a loss of interest...
Category: <span>Inflammation</span>
Nutrients can mimic pharmacological effects of medicines
by Utrecht University Dr. Saskia Braber. Credit: Utrecht University Nutrients can work in surprisingly similar ways as medicines. Pharmacologists from Utrecht University conclude that more knowledge of the similarities between food and medicines could help develop diets to combat diseases. A Mediterranean diet, high-fiber food, and whole fruits and vegetables are well-known elements of healthy nutrition....
New ways to block inflammatory cells implicated in a suite of diseases
by Trinity College Dublin Micrograph showing pulmonary macrophages in a bronchial wash specimen. Diff-Quik stain. Credit: Librepath/Wikimedia Commons, CC BY-SA 3.0 Scientists from the Trinity Biomedical Sciences Institute (TBSI) have discovered two new ways to block inflammatory macrophages—front-line cells in our immune system that cause complications in a suite of diseases, including COVID-19. The scientists have...
Genetic Variants Associated with Visceral Fat Accumulation Correlate with Longevity
It is well established that excess visceral fat is harmful. This tissue is metabolically active, and generates increased chronic inflammation through numerous mechanisms: a greater number of senescent cells; signaling by fat cells that appears similar to that produced by infected cells; increased debris from dead and dying fat cells that provokes the immune system....
Tiny bubbles can be future treatment for inflammation
Scientists hope that tiny sacs of material excreted by cells – so-called extracellular vesicles – can be used to deliver drugs inside the body. Researchers at Karolinska Institutet now show that these nano-bubbles can transport protein drugs that reduce inflammation caused by different diseases. The technique, which is presented in Nature Biomedical Engineering, shows promising...
Childhood and adult chronic spontaneous urticaria: time to develop different management strategies?
LUGANO, 2 October, 2021– New research presented at EADV 30th Congress today unveils key insights on the characteristic differences in chronic spontaneous urticaria (commonly presented as hives) in children versus adults. The findings reveal chronic spontaneous urticaria is less severe in children than in adults, with lower rates of angioedema and thyroid autoimmunity, supporting the idea that...
Glycerin is safe, effective in psoriasis model
by Medical College of Georgia at Augusta University Dr. Wendy Bollag and first author Dr. Vivek Choudhary, MCG physiologist and molecular biologist. Credit: Michael Holahan, Augusta University Patients with psoriasis have reported that glycerin, an inexpensive, harmless, slightly sweet liquid high on the list of ingredients in many skin lotions, is effective at combatting their psoriasis...
First evidence of inflammatory micro clots in blood of individuals suffering from Long COVID
STELLENBOSCH UNIVERSITY IMAGE: FLUORESCENT IMAGE OF HEALTHY BLOOD PLASMA (LEFT) COMPARED TO THE MICRO CLOTS IN THE PLASMA FROM AN INDIVIDUAL WITH LONG-COVID ON THE RIGHT. CREDIT: RESIA PRETORIUS New research indicates that an overload of various inflammatory molecules, literally “trapped” inside insoluble microscopic blood clots (micro clots), might be the cause of some of...
Long-lasting pain relief without opioids: Researchers develop a novel, local treatment for chronic pain
by University at Buffalo Credit: Unsplash/CC0 Public Domain An investigation into the origins of the sensation of pain has led to the development of a novel and durable treatment for inflammatory pain that could be a promising alternative to opioids. The preclinical research was conducted by neuroscientists and pharmacologists, all in the Jacobs School of Medicine...
Link between inflammation and pancreatic cancer development uncovered
by University of Texas M. D. Anderson Cancer Center Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer Institute A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development. According to the study published today in Science, pancreatic...