By Rich Haridy April 11, 2021 New imaging research suggests functional brain network connectivity alterations could explain cognitive problems associated with chronic sinusitis. More than one in 10 adults in the United States suffer from chronic rhinosinusitis, a persistent inflammatory sinus condition. A new brain imaging study is suggesting chronic rhinosinusitis is associated with functional...
by American Heart Association Credit: CC0 Public Domain Testing how well “good” cholesterol particles reduce inflammation may help predict who is at heightened risk to develop cardiovascular disease caused by narrowed arteries, according to research published today in the American Heart Association’s flagship journal Circulation. Assessing levels of high-density lipoprotein (HDL) cholesterol, known as “good cholesterol,” are already a...
by The Scripps Research Institute Scientists at Scripps Research find evidence that antibody treatments in clinical trials for neurodegenerative diseases may trigger an inflammatory response that erodes their positive effects. Pictured: Dopaminergic neurons in red and microglia in green. Credit: Lipton laboratory, Scripps Research A team led by scientists at Scripps Research has made a discovery suggesting that experimental antibody therapies for Parkinson’s...
DUKE UNIVERSITY DURHAM, N.C. -An unfortunate biological “feed-forward” loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers at Duke University and Washington University in Saint Louis. Pain researcher and mechanobiologist Wolfgang Liedtke, a professor of neurology at Duke, partnered with former Duke colleague and cartilage expert Farshid Guilak,...
Researchers have discovered that DNA from the mitochondria – the cell’s “powerhouses” – acts as a danger signal in the body and triggers inflammation in people with sickle cell disease. A better understanding of mitochondrial DNA, long known to circulate in human blood, may provide vital insight into how to stop the underlying chronic inflammation that...
by RCSI Dr Claire McCoy, Senior Lecturer in Immunology at RCSI University of Medicine and Health Sciences. Credit: Patrick Bolger RCSI researchers have discovered a new way to ‘put the brakes’ on excessive inflammation by regulating a type of white blood cell that is critical for our immune system. The discovery has the potential to protect the...
by Johns Hopkins University Johns Hopkins Medicine researchers have identified an immune system protein called interleukin-6 as a possible link between chronic inflammation and frailty in older adults. Credit: Public domain image Chronic inflammation in people age 65 and older may be marked by frequent infections, pain, injuries and slow healing wounds. To make matters worse, the negative...
By Michael Irving March 03, 2021 Tomas Huerta (left) and Sangeeta Chavan (right), researchers on the new study Feinstein Institutes for Medical Research Obesity is one of the most pressing health problems in the world today, but a new study suggests a potential non-invasive treatment. In tests in mice, researchers found that directing ultrasound pulses to the...
The discovery of an “Achilles’ heel” in a type of gut bacteria that causes intestinal inflammation in patients with Crohn’s disease may lead to more targeted therapies for the difficult-to-treat disease, according to researchers at Weill Cornell Medicine and NewYork-Presbyterian. In a study published in Cell Host and Microbe, the investigators showed that patients with Crohn’s disease have an...
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IMAGE: Shown is a transmission electron microscope image of exosomes purified from fluid from the lungs of a patient with COPD. A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for...
