by Adrianna MacPherson, University of Alberta Faculty of Medicine & Dentistry U of A researcher Christopher Power and his team found that administering an anti-inflammatory drug called VX-765 through the nose slowed the progression of multiple sclerosis in a preclinical model. Intranasal administration of an anti-inflammatory drug helped reduce disease progression in a preclinical model of...
by Mike Addelman, University of Manchester A rare genetic condition which causes inflammatory bowel disease can be successfully treated by bone marrow transplant, according to University of Manchester and Manchester University NHS Foundation Trust researchers. The disease, called G6PC3 deficiency, affects around one in a million people and causes inflammation of the bowel, as well as lung...
by University of Luxembourg An international collaboration involving researchers from the Luxembourg Center for Systems Biology (LCSB) at the University of Luxembourg established an association between inflammation and specific genetic mutations in Parkinson’s patients. The study, recently published in the scientific journal Brain, highlights two biomarkers that could be used to assess Parkinson’s disease state and progression. The results...
by Annabel Mansfield, University of South Australia Loved or hated, the humble oat could be the new superfood for cancer patients as international research shows a diet rich in fiber could significantly reduce radiation-induced gut inflammation. Conducted by the University of Gothenburg, Lund University and the University of South Australia, the preclinical study found that dietary oat bran can offset...
by Stony Brook University Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Diet remains an important part of disease prevention and management, and a new study suggests that consumption of fructose may worsen intestinal inflammation common to inflammatory bowel diseases (IBD). Led by David Montrose, Ph.D., of the...
RUDN UNIVERSITY IMAGE: A GENETICIST FROM RUDN UNIVERSITY STUDIED THE EFFECT OF BIFIDOBACTERIUM (INTESTINAL BACTERIA) ON THE INFLAMMATORY PROCESS AND DISCOVERED THAT THEIR SURFACE PROTEIN IS CAPABLE OF STOPPING EXCESSIVE OR UNCONTROLLABLE INFLAMMATION. CREDIT: RUDN UNIVERISTY A geneticist from RUDN University studied the effect of Bifidobacterium (intestinal bacteria) on the inflammatory process and discovered that...
by Todd Bates, Rutgers University This drug delivery system includes a porous biodegradable platform that can reduce nervous tissue inflammation and may help treat spinal cord injuries and other neurological disorders. A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and...
E-cigarette, or vaping, associated lung injury (EVALI) has sickened thousands of people, most under the age of 35. Studies have linked vitamin E acetate, an oily substance in some vaping liquids, to the disorder. Now, researchers reporting in ACS’ Chemical Research in Toxicology have uncovered a possible mechanism: Vitamin E acetate could increase the fluidity of lung...
SALK INSTITUTE IMAGE: FROM LEFT: REUBEN SHAW AND JEANINE VAN NOSTRAND. The diabetes drug metformin–derived from a lilac plant that’s been used medicinally for more than a thousand years–has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 diabetes. Yet scientists don’t fully understand how the drug is...
by University of Helsinki A new model of ANGPT2-mediated TIE2 and TIE1 clustering and activation at atomic resolution. Credit: VM Leppanen et al., Sci. Transl. Med. 12, eaax8013 (2020) The Human Molecular Genetics laboratory of the de Duve Institute (UCLouvain), headed by Professor Miikka Vikkula, recently identified mutations in a novel gene, ANGPT2, responsible for primary lymphedema....
