September 18, 2024 NIH-supported clinical trial is the first positive trial for treatment of hereditary hemorrhagic telangiectasia. A clinical trial supported by the National Institutes of Health (NIH) was stopped early after researchers found sufficient evidence that a drug used to treat bone marrow cancer and Kaposi sarcoma is safe and effective in treating hereditary...
Category: <span>Pharmaceutical Updates</span>
Post
New migraine drugs less effective than previous generation of triptan meds
MigraineA meta-analysis of 137 trials of migraine drugs indicates that the newest class of treatments are less effective than the previous generation of triptan drugs in relieving acute headaches. A study from The BMJ indicates that the newest class of migraine drugs—which includes Pfizer’s Nurtec, AbbVie’s Ubrelvy and Eli Lilly’s Reyvow—is less effective in the...
Post
Clinical trial demonstrates success in treating rare blood disorder
September 18, 2024 by Cleveland Clinic Credit: CC0 Public DomainA clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than one in 5,000 people worldwide. The trial, led by Keith McCrae, M.D., of Cleveland Clinic, was stopped early...
Post
Ground squirrel study points to potential development of a cataract drug
September 18, 2024 by Kathryn DeMott, National Institutes of Health GS lens opacity is reversed during the hypothermia-rewarming cycle. Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI169666Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye’s lens that occurs...
Post
NANOPARTICLES DELIVER DRUGS TO KILL CANCER CELLS IN MICE
SEPTEMBER 17TH, 2024POSTED BY U. CHICAGO(Credit: Getty Images) TAGS : CANCER, NANOTECHNOLOGYUNIVERSITY : UNIVERSITY OF CHICAGO Researchers have developed a nanomedicine that increases the penetration and accumulation of chemotherapy drugs in tumor tissues and effectively kills cancer cells in mice. The study in Science Advances addresses a limitation of chemotherapy. Although chemotherapy is the primary...
Post
DEADLY SNAIL VENOM COULD MAKE DIABETES MEDICINES BETTER
SEPTEMBER 17TH, 2024POSTED BY SOPHIA FRIESEN – UNIVERSITY OF UTAH(Credit: Getty Images) TAGS DRUG : DEVELOPMENT, MEDICATIONS, SNAILS, VENOMUNIVERSITY : UNIVERSITY OF UTAH Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet. Researchers have identified a...
Post
Some people with MS may need earlier, higher-dose meds, study shows
September 18, 2024 by Dennis Thompson Early, aggressive treatment of brain lesions caused by multiple sclerosis could help ward off faster decline in patients, a new study finds. Such treatment could prevent or potentially cure paramagnetic rim lesions (PRL), areas of chronic brain inflammation that are linked to more rapid deterioration in MS patients, researchers...
Post
Medical marijuana users see short-term gains in health-related quality of life, study finds
September 17, 2024 by Philadelphia College of Osteopathic Medicine Changes* in Health-Related Quality of Life (HRQoL) Over Three Months of Medical Marijuana Use (N = 399). * Paired-samples t-tests, all scales significant at <.001. HRQoL measured by the Short Form-36. Credit: Journal of Cannabis Research (2024). DOI: 10.1186/s42238-024-00245-9A study of hundreds of people using medical...
Post
New study increases understanding of HIV drug’s negative effects on the brain
News Release 17-Sep-2024 Findings pave the way toward mitigating some drugs’ toxic effects Peer-Reviewed PublicationUniversity of Maryland Baltimore County image: This is figure 4 from a paper in ACS Pharmacology & Translational Science that used a novel approach to show changes in lipid metabolism and protein expression as a result of treatment with the HIV...
Post
Study suggests blackcurrant supplementation mitigates postmenopausal bone loss
September 17, 2024 by Anna Zarra Aldrich, University of Connecticut Credit: Wikimedia CommonsAs we age, our bones lose density and become more fragile, putting us in danger of breaks and fractures. This is especially a concern among post-menopausal women who generally have much greater losses in bone density than men in their age group. Ock...