The MucoJet technology is designed to be self-administered. Patients could one day self-administer vaccines using a needleless, pill-sized technology that jet-releases a stream of vaccine inside the mouth, according to a proof-of-concept study conducted at UC Berkeley. The study did not test vaccine delivery in people, but demonstrated that the technology, called MucoJet, is capable...
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Prostate therapy without surgery: Thousands of men to benefit from new technique that uses plastic beads to block blood supply and shrink the enlarged gland
Successful trial in Portugal being followed up in UK with results due this year If it is successful the technique could be rolled out for routine use on the NHS Researchers expect it to largely replace surgery as the standard treatment Tens of thousands of men could benefit from a breakthrough prostate treatment announced today....
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Researchers Have Found a “Reset Button” for Aging Cells
IN BRIEF Induced pluripotent stem (iPS) cells may be the key to reversing aging in hematopoietic stem cells. The technique is also particularly useful for combating blood-related cancers and other disorders. FIGHTING DISEASE BEFORE IT STRIKES From revitalizing heartbeats and increasing longevity, to removing disorders via gene editing, blood-borne challenges are approached with new solutions as quickly as we can innovate them....
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Powerful RNA-based technology could help shape the future of therapeutic antibodies
Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are large, complex proteins that can be expensive to manufacture. Now, a team led by scientists from the Perelman School of Medicine...
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Virtual Reality Job Interview Training for Veterans with Post Traumatic Stress Disorder
Abstract BACKGROUND Veterans with posttraumatic stress disorder (PTSD) have low employment rates and the job interview presents a critical barrier for them to obtain competitive employment. OBJECTIVE To evaluate the acceptability and efficacy of virtual reality job interview training (VR-JIT) among veterans with PTSD via a small randomized controlled trial (n=23 VR-JIT trainees, n=10 waitlist...
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Heart drug improves or stabilizes heart function in Duchenne muscular dystrophy
Human heart. Researchers at The Ohio State University Ross Heart Hospital and Nationwide Children’s Hospital have shown early treatment with the heart failure medication eplerenone can improve heart function in young boys with Duchenne muscular dystrophy (DMD) and stabilize heart function in older boys with the disease. The results of their study are published...
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New treatment for fatty liver disease and type 2 diabetes burns up fat in liver
A new treatment for nonalcoholic fatty liver disease and type 2 diabetes is being developed for clinical trial in Sweden. Researchers in Sweden are planning the clinical trial of a new treatment for nonalcoholic fatty liver disease and type 2 diabetes which harnesses liver cells’ own ability to burn accumulated fats. In a study involving...
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Biosimilar of costly inflammatory bowel disease therapy found safe and effective
Treatment of Crohn’s disease and ulcerative colitis has been greatly improved by the introduction of biologic therapies such as infliximab (which targets tumour necrosis factor alpha), but at considerable cost. A recent analysis of results from 11 published studies including 829 patients shows that a new and lower-cost biosimilar for infliximab—called CT-P13 (Remsima/Inflectra)—has excellent clinical...
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Protein HMGB1 may be the key to better asthma treatment
A new study, published in the Journal of Allergy and Clinical Immunology, investigates a potential new approach to designing drugs for the treatment of asthma. Better interventions could be on the horizon. With asthma cases on the rise, research looking at novel drug targets is more important than ever. Asthma causes an individual’s airways to become inflamed...
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Autoimmune disease: Could modified red blood cells lead to new treatments?
New treatments that prevent and alleviate autoimmune diseases may come from using red blood cells to carry disease-specific proteins that retrain the immune system. So concludes a study that shows such an approach works in mice with multiple sclerosis and type 1 diabetes. The researchers say that their method of using red blood cells to...