by The Hospital for Sick Children Graphical abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.10.009 Researchers from The Hospital for Sick Children (SickKids) have uncovered new genes and genetic changes associated with autism spectrum disorder (ASD) in the largest autism whole genome sequencing analysis to date, providing better understanding into the ‘genomic architecture’ that underlies this disorder. The study,...
by Tel Aviv University Credit: Pixabay/CC0 Public Domain A new study from Tel Aviv University proposes a new learning method for people with autism that may accelerate the learning process and even significantly improve capabilities in terms of visual perception. According to the researchers, improving the perceptual capacity of people with autism is often a...
Fragile X syndrome, or FXS, a leading genetic cause of autism, affects around one in 4,000 males and one in 6,000 females. Its symptoms include increased anxiety, intellectual disability, repetitive behaviors, social communication deficits, and abnormal sensory processing. People living with FXS generally lack the fragile X mental retardation 1 gene, or Fmr1, in their brain cells....
by Ellen Goldbaum, University at Buffalo Fig. 1: ASH1L expression and H3K4me3 level are significantly decreased in PFC of postmortem ASD patients, which is replicated by knockdown of Ash1L in PFC of young mice. a Quantitative PCR data showing ASH1L mRNA levels in postmortem PFC tissues from control humans vs. idiopathic ASD patients. n = 12 humans (10 M,2 F)/group,...
by Purdue University Credit: Pixabay/CC0 Public Domain Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies have revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, are a leading cause of autism. Overactive sodium channels in the neuron cause...
by University of Geneva Example of ‘skeleton’ extraction using OpenPose on an image extracted from the recording of a social scene: (A) OpenPose keypoints overlaid on the video recording (B). OpenPose keypoints over a black background, preserving the bare minimum of scene features necessary to identify the social interaction. Credit: Kojovic, Natraj, Mohanty, Maillart, Schaer Individuals...
by Curtin University Credit: CC0 Public Domain Mothers of children with autism who delayed their subsequent pregnancy by 2.5 to three years reduced the likelihood of their next child also being diagnosed on the spectrum, new research shows. The Curtin University research in collaboration with the Telethon Kids Institute, published in Autism Research, investigated more than 925,000...
by Centre for Addiction and Mental Health Credit: CC0 Public Domain One of the biggest longitudinal research studies of its kind in the world led by The Hospital for Sick Children (SickKids) and the Centre for Addiction and Mental Health (CAMH) suggests that positive outcomes for children with autism spectrum disorder (ASD) are more common than...
Autism spectrum disorder, estimated to affect one in 54 children in the United States, encompasses a range of complex neurodevelopmental conditions that typically emerge in the first few years of life. Yet for a variety of reasons, these conditions could be challenging to diagnose early when interventions are most likely to avert or mitigate some of the more...
UNIVERSITY OF QUEENSLAND A deficiency in Vitamin D on the mother’s side could explain why Autism spectrum disorder is three times more common in boys, say researchers from The University of Queensland. In their latest study, Professor Darryl Eyles and Dr Asad Ali from UQ’s Queensland Brain Institute found vitamin D deficiency during pregnancy caused an increase in testosterone in the developing brain of...
