MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY IMAGE: FORMINS ARE MADE OF TWO IDENTICAL PARTS (RED, ORANGE) THAT ENCIRCLE THE ACTIN (GREY) FILAMENT IN A RING-LIKE CONFORMATION.CREDIT: MPI OF MOLECULAR PHYSIOLOGY Joining forces “Our discovery allows us to interpret decades of biochemical studies on formins through new lenses, which answers many long-standing, open questions in this...
Category: <span>Research Updates</span>
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Could breath analysis help with gut issues?
Content by Owlstone Medical LtdReviewed by Louis Castel Pharmaforum, the pharmaceutical industry’s online forum established to exchange knowledge, insights, and advances in the field, has recently published an article by Owlstone CEO Billy Boyle, and Scientific Content Writer Dr. Madeleine Ball. The piece titled, ‘How breath analysis could help those living with gut health issues...
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Gold Nanoparticles Improve Accuracy of Infectious Disease Testing
Composite polymer particles adorned with gold nanoparticles could improve the accuracy of infectious disease testing. Original story from Tohoku University Purple circles with small protrusions on a black background.GNDP particles Credit: Hiroshi Yabu By harnessing the power of composite polymer particles adorned with gold nanoparticles, a group of researchers have delivered a more accurate means...
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Alzheimer’s Starts Earlier and Progresses Faster in People With Down Syndrome
A new study revealed that Alzheimer’s disease starts earlier and progresses faster in people with Down syndrome.Original story from Washington University School of Medicine in St Louis A scientist in a white lab coat helps a person with Down syndrome into a brain scan machine.Washington University senior clinical research coordinator Brittany Nelson (front) helps study...
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AI-Based Biomarker for Aortic Stenosis Found
Yale investigators from the cardiovascular medicine section have identified a new artificial intelligence (AI)-based video biomarker to identify those who might develop and have rapidly worsening aortic stenosis.This research was highlighted in a new paper, “A Multimodality Video-Based AI Biomarker For Aortic Stenosis Development And Progression,” published in JAMA Cardiology. More than 1.5 million people...
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How the inflamed brain becomes disconnected after a stroke
by Levi Gadye, University of California, San Francisco The brain’s neurons (yellow) connect with one another using a vast network of neural wires, called neurites. Credit: Swanson Lab/University of California, San FranciscoWhether reeling from a sudden stroke or buckling under the sustained assault of Alzheimer’s, the brain becomes inflamed, leading to cognitive problems and even...
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Brain vesicles found to contain selectively packaged, full-length mRNA
by Sanford-Burnham Prebys This portrait of extracellular vesicles was taken using confocal laser scanning microscopy. The membrane was stained with fluorescent dye. Image titled “Exosomes” courtesy of Tomaž Einfalt, University of Basel, under Creative Commons BY-NC-ND license. Credit: Tomaž EinfaltScientists at Sanford Burnham Prebys have demonstrated that vesicles traveling between cells in the brain carry...
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New insights into cholesterol dynamics shed light on neurodegenerative disease
by Lisbeth Heilesen, Aarhus University New knowledge about cholesterol contribute to the understanding of the neurodegenerative Niemann-Pick type C disease – also called “childhood Alzheimer’s” Credit: Mikael WinklerUsually, the word “cholesterol” prompts a negative reaction because of its role in cardiovascular disease. While this is true, cholesterol is also vital for cells to function correctly—for...
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Cognitive decline may be detected using network analysis, according to Concordia researchers
CONCORDIA UNIVERSITY IMAGE: NATALIE PHILLIPS AND NICHOLAS GRUNDEN: “NETWORK ANALYSIS HELPS US READ BETWEEN THE LINES, BECAUSE WE CAN LOOK AT THE INTERRELATIONSHIPS BETWEEN ALL OF THE VARIABLES AT THE SAME TIME.”CREDIT: CONCORDIA UNIVERSITY We all lose our car keys or our glasses from time to time. Most people would be correct to laugh it...
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Digital Twin Allows for Tailored Medication
Individual patients with autoimmune diseases can receive tailored medication by computationally treating their so-called digital twins with thousands of medications. This is according to an international study published in Genome Medicine by researchers from Karolinska Institutet. What does your publication show?“It is possible to construct a digital twin of an individual patient’s autoimmune disease. This...