by Keck School of Medicine of USC Credit: AI-generated imageIn one of the largest ever gene-environment interaction studies of red meat and colorectal cancer, which explored the impact of red meat consumption on a person’s cancer risk based on their genotype, researchers have identified two genetic markers that may help explain the association between the...
by Walter and Eliza Hall Institute of Medical Research machinery shown by the fibrillarin protein (green) in the nucleus (blue) that stimulates the nucleolar stress response and initiates leukaemia cell death. Credit: Peter MacResearchers have found a new way to potentially treat one of the most common forms of acute lymphoblastic leukemia. The study, led...
by Wiley Credit: Pavel Danilyuk from PexelsNew research indicates that individuals with persistent and worsening metabolic syndrome—which encompasses conditions such as high blood pressure, elevated blood sugar, excess abdominal fat, and abnormal cholesterol—face an elevated risk of developing various types of cancer. The findings are published in a paper titled “The association of metabolic syndrome...
by Ernie Mundell A cancer drug duo more than doubled the survival of people battling the most common form of advanced bladder cancer, trial results show. Patients who took a combo of meds called EV+P—enfortumab vedotin and pembrolizumab (Keytruda)—had an average of 31.5 months survival, compared to just over 16 months for those on standard...
by Centro de Investigación Médica Aplicada (CIMA) Universidad de Navarra Replication stress induces lncRNAs associated to replicating chromatin. a (Top) Mechanism of action of hydroxyurea (HU) RNR: ribonucleotide reductase. (Bottom) Immunoblot analysis HCT116 cells treated with HU 1 mM for 8 h followed by 3 h recovery shows the reversible effect of HU on replication stress markers p-ATR,...
Researchers are reporting that some early-stage cancer cells activate a gene that helps hide them from the body’s immune response.They say that identifying this uptick in gene expression among cancer cells could lead to new pathways for early diagnosis and future treatment of colon cancer.Experts say more research is needed, however, to confirm these findings...
by University of Vienna Immunofluorescence image of the expression of PHGDH (red) and CD3 T cells (green) in cryosectioned AE17 mesothelioma. Credit: Zhengnan CaiA study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic...
Dr Catherine Wu has paved the way for the development of cancer vaccinesShe ‘drew a picture of [myself] making a cure for cancer’ in second grade By CAITLIN TILLEY, HEALTH REPORTER FOR DAILYMAIL.COM Dr Wu’s obsession with the immune system began after she watched bone marrow transplants as a medical internDr Wu’s obsession with the...
Peer-Reviewed Publication JOHNS HOPKINS MEDICINE FOR IMMEDIATE RELEASE Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients’ immune systems fight back against cancer, according to a study by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. The...
POSTED BY ANDY FELL-UC DAVIS Researchers have identified a protein linked to metastasis in pancreatic cancer. Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed. Severe pancreatic cancer is associated with metastasis, and it is this spread of secondary tumors...
