The removal of the protein BECLIN1 causes a condition with similarities to IBD. Original story from La Trobe University La Trobe University researchers have identified a protein that is integral to gut health, providing an important lead in the search for a treatment for people with Inflammatory Bowel Disease (IBD). Research published in Communications Biology,...
by Anna Björklund, Identification of a conformational switch in c-MYC. a Overview of the MD strategy employed to identify regions that exhibit probe-induced conformational changes. b Normalized frequency distribution of Rg computed from the ensemble of structures generated from explicit solvent MD simulations in water (black) and water + benzene (red) for all nine c-MYC...
University of Sussex led research identifies protein (PANK4) as an obstacle that blocks cancer cells from responding to chemotherapeutic treatment for glioblastomaPeer-Reviewed Publication UNIVERSITY OF SUSSEX New research by the University of Sussex could help to increase life expectancy and improve treatment for an aggressive brain cancer, which impacts thousands of people every year in...
Scientists investigate how the Cpeb4 protein mediates the production of osteoclasts, which are involved in bone and joint diseases, including osteoporosis.Peer-Reviewed Publication TOKYO UNIVERSITY OF SCIENCE A RECENT STUDY BY TUS RESEARCHERS REVEAL THAT THE CPEB4 PROTEIN MAY HAVE A ROLE IN REGULATING OSTEOCLAST DIFFERENTIATION. THIS, IN TURN, COULD LEAD TO THE DEVELOPMENT OF NEW...
French musician Guilhem Gallart, a member of the Fonky Family, is seen here with his partner Wahiba; he was diagnosed with ALS in 2015. A new treatment shows promise against the deadly neurodegenerative disease ALS, a study based on mice showed Tuesday. Amyotrophic lateral sclerosis, sometimes called Lou Gehrig’s disease after the famous baseball player,...
Osaka UniversityJust as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell, for example, mitochondria power the cell and lysosomes keep the cell tidy. Although damage to these two organelles has been linked to aging, cellular...
by University of Massachusetts Amherst Credit: Unsplash/CC0 Public Domain While we often think of diseases as caused by foreign bodies—bacteria or viruses—there are hundreds of diseases affecting humans that result from errors in cellular production of proteins. A team of researchers led by the University of Massachusetts Amherst leveraged the power of cutting-edge technology, including an...
by Monash University Credit: Pixabay/CC0 Public Domain The global rise in obesity and diabetes is leading to an epidemic in fatty liver disease affecting 20%–30% of the world’s population. Almost a third of people with fatty liver disease go on to develop an advanced form of the disease, known as non-alcoholic steatohepatitis (NASH) that can progress...
by UK Research and Innovation Credit: UK Research and Innovation Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids. In most of these diseases, researchers have identified the proteins that aggregate, allowing them to target these proteins for diagnostic tests and treatments. But, in around 10% of cases of frontotemporal dementia, scientists had...
by Australian National University 3D printed stencil of the DECTIN-1 protein’s structure. Credit: Tracey Nearmy/ANU A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research...
