Richard Mark Kirkner SAN FRANCISCO ― A large observational registry study of almost 100,000 eyes has found that the diabetes drug semaglutide, a GLP-1 agonist recently approved for weight loss, does not worsen the progression of potentially vision-threatening diabetic retinopathy in the long term in patients taking the drug. However, the researchers said, the findings...
Category: <span>Diabetes</span>
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Stem cell ‘messages’ fast-track healing of diabetic wounds
by TranSpread Credit: Burns & Trauma (2024). DOI: 10.1093/burnst/tkae001The increasing prevalence of diabetes worldwide has led to a rise in diabetic wounds, such as diabetic foot ulcers, which are challenging to treat and can result in amputation. Traditional treatments have limited effectiveness, underscoring the urgent need for innovative solutions. In a new study published in...
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Could a ‘DNA diet’ help to reduce health risks linked to high blood sugar?
Peer-Reviewed Publication IMPERIAL COLLEGE LONDON The findings come from a small Imperial College London and DnaNudge pilot study involving 148 people with high blood sugar levels who were at risk of going on to develop type 2 diabetes (T2D). It found that following personalised dietary advice informed by genetic information, in combination with face-to-face dietary...
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Q&A: How a potential treatment for Alzheimer’s disease could also work for type 2 diabetes
by Sarah McQuate, University of Washington Microscopy image of beta cells making IAPP (left) and IAPP plus one of the team’s synthetic peptides (right). Credit: Protein Science (2023). DOI: 10.1002/pro.4854Of the 38 million Americans who have diabetes, at least 90% have type 2, according to the Centers for Disease Control and Prevention. Type 2 diabetes occurs...
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Insulin-inhibitory receptor research offers hope for type 2 diabetes therapy
by Verena Schulz, Helmholtz Association of German Research Centres Central inceptor immunoreactivity is restricted to neurons, including those regulating energy and glucose metabolism. Credit: Nature Metabolism (2024). DOI: 10.1038/s42255-024-00991-3Research targeting the insulin-inhibitory receptor, or inceptor, unveils promising avenues for beta cell protection, offering hope for causal diabetes therapy. A novel study in mice with diet-induced obesity...
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Once-Weekly Insulin Better Than Daily in Type 2 Diabetes
Drishti Agarwal TOPLINE:Once-weekly insulin icodec shows a higher glycated A1c reduction than once-daily basal insulin analogs in patients with type 2 diabetes (T2D), without major safety concerns. METHODOLOGY:A meta-analysis of five phase 3 ONWARDS randomized controlled trials included 3764 patients with T2D.The trials compared the effects of the weekly insulin icodec with those of the...
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Researchers uncover potential treatment for cardiovascular complications from type 2 diabetes
by University of Missouri Graphical abstract. Credit: American Journal of Physiology-Heart and Circulatory Physiology (2023). DOI: 10.1152/ajpheart.00337.2023New research at the Roy Blunt NextGen Precision Health building has discovered a potential treatment for an underlying cause of cardiovascular disease in people with type 2 diabetes. More than 30 million Americans live with type 2 diabetes. One common...
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New Marker of Cardiovascular Risk Discovered in T2D
Anne-Gaëlle Moulun A significant quantity of dysfunctional monocytes appears to indicate poor cardiovascular prognosis in patients with type 2 diabetes, according to a new publication. Nicolas Venteclef, PhD, director of an Inserm institute for diabetes research at Necker Enfants Malades Hospital in Paris, France, led the research. Quantifying InflammationPatients with type 2 diabetes have about...
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Researchers reveal how diabetes weakens gum defense
by Pusan National University The study associating periodontitis (PD) and diabetes mellitus (DM) using single-cell RNA analysis offers the first immunological explanation, revealing altered immune cell function and suggesting PD as a potential precursor to DM through the RESISTIN pathway. Credit: Yun Hak Kim from Pusan National UniversityPeriodontitis (PD) is a common complication in individuals with...
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Gargling away the bad bacteria in type 2 diabetes
Researchers from Osaka University find that gargling with an antiseptic mouthwash can reduce ‘bad’ bacteria in the mouths of people with type 2 diabetes, and may lead to better control of their blood sugarPeer-Reviewed Publication OSAKA UNIVERSITY MECHANISM OF TYPE 2 DIABETES MELLITUS IMPROVEMENT BY GARGLING WITH MOUTHWASH CREDIT: SAAYA MATAYOSHI Osaka, Japan – More...