Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation. The research team, led by clinical researchers at Intermountain Healthcare’s Intermountain Medical Center in Salt Lake City,...
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New research into delaying the onset of motor neurone disease shows positive results
New research conducted by scientists at the University of Sheffield into a drug candidate which could help to delay the onset of motor neurone disease has shown encouraging early results. The drug candidate was discovered by the British artificial intelligence company BenevolentAI. The study, which was led by Dr Richard Mead and Dr Laura Ferraiuolo from...
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Statins beneficial for the heart, beyond just lowering cholesterol
New research has revealed that in addition to lowering cholesterol, statins may have improve heart structure and function In recent years, statins have come under fire with indications side-effects from these drugs could potentially outweigh any benefits in low-risk patients. While several follow up studies showed the negative side-effects of statins to be relatively minimal compared to...
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Researchers studying century-old drug in potential new approach to autism
Developed in 1916 by German dye manufacturers Frederich Bayer and Co., Bayer 205 (later renamed suramin) was found to be effective against parasitic trypanosomes responsible for African sleeping sickness (trypanosomiasis). This bottle of …more In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a...
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Blocking cancer-specific mutations in leukemia and brain tumors
Candidate drug BAY1436032 (yellow) binds to the mutated enzyme IDH1. The substitution of a single amino acid in a metabolic enzyme can be the cause of various types of cancer. Scientists from the German Cancer Research Center and Heidelberg University Hospital, collaborating with Bayer AG, have now been able to develop a candidate for...
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Cold virus, stem cells tested to destroy deadly brain cancer
Killer T cells surround a cancer cell. A first-of-a-kind neural stem cell therapy that works with a common cold virus to seek out and attack a lethal and aggressive brain cancer is being tested at Northwestern Medicine in a Phase I clinical trial for patients newly diagnosed with malignant glioma. The novel drug to...
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Chemical array draws out malignant cells to guide individualized cancer treatment
A chemical array screens for malignant melanoma cell types. Each dot contains a different combination of protein segments derived from the tumor environment. Melanoma is a particularly difficult cancer to treat once it has metastasized, spreading throughout the body. University of Illinois researchers are using chemistry to find the deadly, elusive malignant cells within...
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Researchers Discover The Proteins Responsible For Cancer Metastasis And How To Control Them
Researchers Discover The Proteins Responsible For Cancer Metastasis And How To Control Them Cancer treatments do not always produce positive results despite advanced treatments and procedures designed to fight off the disease. Even with patients previously cleared of the disease, things could suddenly turn upside down when the tumors come back and quickly spread to other parts of the...
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Unmasking rogue cells in the immune system
Genetic alteration of a mouse embryo to “knock down” — which is to disrupt — the JunB gene, which is then going to be unavailable for the immune system cells to use. The immune system is a formidable defense against microbial intruders, identifying and eliminating threats through an extremely intricate and adaptable network of...
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Study makes breakthrough in understanding of proteins and their impact on immune system
Researchers at the University of Birmingham have made a breakthrough in the understanding of how our genetic make-up can impact on the activity of the immune system and our ability to fight cancer. The study, conducted in conjunction with researchers from Birmingham’s Queen Elizabeth Hospital, was published in Science Signaling and focusses on a protein called ULBP6. Proteins are...