IN BRIEF Researchers from MIT have developed a new way of delivering multiple vaccine doses in just one injection using a new drug-carrying particle. Designing the particles themselves required an equally innovative solution that used 3D fabrication. SEALED AND TIMED Nobody enjoys getting a shot; especially when you have to get more than one. Currently,...
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Immunotherapy for lung cancer: What you need to know
Immunotherapy, also known as biologic therapy, may benefit people fighting certain kinds of lung cancer. This treatment option uses medicines to stimulate the body’s immune system so that it can fight the cancer cells more effectively. Immunotherapy has changed the way doctors treat many types of cancer, including lung cancer. In this article, we look at how immunotherapy...
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Strategy might prevent infections in patients with spinal cord injuries
New research led by The Ohio State University Wexner Medical Center found a potential therapeutic strategy to prevent infections in patients with spinal cord injuries. This research using mice with spinal cord injuries breaks new ground in the development of treatments to prevent and reduce the incidence of infections without the use of antibiotics, and...
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Researchers compose guidelines for handling CAR T cell side effects
Immune-cell based therapies opening a new frontier for cancer treatment carry unique, potentially lethal side effects that provide a new challenge for oncologists, one addressed by a team led by clinicians at The University of Texas MD Anderson Cancer Center with proposed guidelines for systematically dealing with the toxicities of these drugs. Their work, published...
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Inhibitors support immune therapy for leukemia
Bone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. New immune therapies are considered a promising lead for treating recurring acute myeloid leukemia (AML). Antibodies are able to eliminate even those cancer cells that cannot be removed via regular therapies. Scientists from the German Cancer Consortium (DKTK) and the Munich University...
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Immunotherapy treatment option for selected breast cancer patients, genetic study suggests
Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumours, researchers at the Wellcome Trust Sanger Institute and their collaborators find. Published today (13 September) in Cancer Research, scientists identify particular genetic changes in a DNA repair mechanism in breast cancer. The results open up the possibility to another therapy...
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Cholesterol-like molecules switch off the engine in cancer-targeting ‘Natural Killer’ cells
Scientists have just discovered how the engine that powers cancer-killing cells functions. Crucially, their research also highlights how that engine is fuelled and that cholesterol-like molecules, called oxysterols, act as a “cut-off” switch making it hard for our ‘Natural Killer’ cells to win the war against cancer. The scientists, led by Ussher Assistant Professor in...
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Immunotherapy treatment option for selected breast cancer patients, genetic study suggests
Existing immunotherapy drugs could help some breast cancer patients, based on the genetic changes in their tumors Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumours, researchers at the Wellcome Trust Sanger Institute and their collaborators find. Published today (13 September) in Cancer Research, scientists identify particular genetic changes...
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Immune system linked to alcohol drinking behaviour
Researchers from the University of Adelaide have found a new link between the brain’s immune system and the desire to drink alcohol in the evening. In laboratory studies using mice, researchers have been able to switch off the impulse to drink alcohol by giving mice a drug that blocks a specific response from the immune system in the...
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Transmitter chip helps doctors track swallowable electronics through the body
The ATOMS chip can ping its location in the body in response to an MRI scan, allowing doctors to one day keep track of medical nanobots inside patients We could be in for a Fantastic Voyage-style future where tiny medical devices swim through our bodies to deliver drugs or diagnose diseases, but keeping track of all those...