Johannes F.E. Mann, M.D., from the Friedrich Alexander University of Erlangen in Germany, and colleagues reported the prespecified renal outcomes of a randomized controlled trial involving patients with type 2 diabetes receiving usual care who were assigned to liraglutide or placebo. A total of 9,340 patients were randomized and followed for a median of 3.84 years. The researchers found...
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Study: Drug may curb female infertility from cancer treatments
An existing drug may one day protect premenopausal women from life-altering infertility that commonly follows cancer treatments, according to a new study. Women who are treated for cancer with radiation or certain chemotherapy drugs are commonly rendered sterile. According to a 2006 study from Weill Cornell Medicine, nearly 40 percent of all female breast cancer survivors...
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Magnesium cream could combat high blood pressure without the need to take pills
A study has found magnesium lotion boosts levels of the mineral in the blood People with higher than average blood pressure can be deficient in magnesium It may lower hypertension by helping the body to regulate blood flow Good news for people do not like taking pills or have difficulty ingesting them Magnesium cream could...
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Parkinson’s: Asthma drugs may cut risk by a third
A research team from the University of Bergen in Norway, in collaboration with scientists at Harvard University in Cambridge, MA, examined the effect of 1,000 different medications to see which ones may lower or increase the risk of Parkinson’s disease. The first author of the study is Shuchi Mittal, of Harvard Medical School, and the findings were...
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Using asthma inhalers HALVES the risk of developing Parkinson’s disease in old age, ‘landmark’ study finds
It is believed the drug stops abnormal protein clumps accumulating in the brain The findings were made by a team of Norwegian and Harvard University experts They hope it could lead to potential new treatments for the incurable disease Asthma inhalers may protect patients from Parkinson’s disease, a major new study suggests. Full of salbutamol,...
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Blunting CRISPR’s ‘scissors’ gives new insight into autoimmune disorders
Each one of our cells has the same 22,000 or so genes in its genome, but each uses different combinations of those same genes, turning them on and off as their role and situation demand. It is these patterns of expressed and repressed genes that determine what kind of cell—kidney, brain, skin, heart—each will become....
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Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers
Abstract Therapies based on immune cells have been applied for diseases ranging from cancer to diabetes. However, the viral and electroporation methods used to create cytoreagents are complex and expensive. Consequently, we develop targeted mRNA nanocarriers that are simply mixed with cells to reprogram them via transient expression. Here, we describe three examples to establish...
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Researchers discover new immunotherapy combination effective at killing cancer cells
Immunotherapy is an emerging field in the global fight against cancer, even though scientists and clinicians have been working for decades to find ways to help the body’s immune system detect and attack cancerous cells. Doug Mahoney’s lab at the University of Calgary recently discovered an immunotherapy that uses existing cancer drugs in a whole...
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Bacterial cell wall mopping agents could treat chronic inflammatory diseases like type 2 diabetes
Bacteria may be responsible for more than we suspect. Especially when it comes to inflammatory diseases such as type 2 diabetes. Prof. Resia Pretorius from Stellenbosch University (SU) in South Africa and Prof. Douglas Kell from The University of Manchester have conducted a series of studies that are drastically changing the way scientists think about...
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Researchers makes ‘natural born killer’ cell discovery
An unexpected role for a white blood cell called the Natural Killer (NK) cell – a critical cell for ridding the body of infection and cancer, has been discovered by researchers at New Zealand’s University of Otago. The NK cell is a “vigilante” killer – a white blood cell that destroys invaders and cancer cells through a...