Cancer cells. A study by scientists at the University of Arizona and the University of Pittsburgh may hold the key to targeting dormant—or inactive —cancer cells, which are resistant to chemotherapy and other treatments. The results were published today in the journal Cell Reports. Cells can enter a sleeplike state known as quiescence, during which they...
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Russian scientist finds a new way to predict cancer development
IMAGE: ALEKSEY V. BELIKOV, A SCIENTIST FROM THE MIPT LABORATORY OF INNOVATIVE MEDICINE AND AGROBIOTECHNOLOGY, USED THE PUBLICLY AVAILABLE DATA ON 20 MILLION CANCER CASES AND EXAMINED 16 PROBABILITY DISTRIBUTIONS, FINDING… view more A scientist from the Moscow Institute of Physics and Technology (MIPT) has proposed a model that can predict the number of key carcinogenic events...
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People of Mexican decent in US have more liver cancer risk factors than those living in Mexico
Mexican-Americans living in the United States demonstrated more risk factors for liver cancer than their counterparts in Mexico, according to results of a study presented at the 10th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held here Sept. 25-28. “Liver cancer incidence and mortality have been...
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Scientists restore tumor-fighting structure to mutated breast cancer proteins
Scientists at the Virginia Tech Carilion Research Institute have successfully determined the full architecture of the breast cancer susceptibility protein (BRCA1) for the first time. This three-dimensional information provides a potential pathway to restore the BRCA1 protein’s cancer-fighting abilities, even after it suffers damage. Their results, published this week in Science Advances, suggest a new paradigm...
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‘Capicua’ gene plays a key role in T-cell acute lymphoblastic leukaemia
T-ALL mouse model with inactivated CIC/CAPICUA (staining with CD3 antibodies highlighting aberrant T cells). Researchers at the Spanish National Cancer Research Centre (CNIO) have discovered a genetic alteration that is directly involved in at least 10 percent of cases of a common cancer in children, T-cell acute lymphoblastic leukaemia. In a paper published this...
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New study offers novel treatment strategy for patients with colon cancer
Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. In a new study, researchers demonstrate for the first time that a previously uncharacterized protein is increased in colon cancer. The protein is immunoglobulin containing proline rich receptor-1 (IGPR-1) which was recently identified in the same laboratory as a cell adhesion molecule. The new findings, reported...
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Promising modification of the intestinal flora in colon cancer
Living lactic acid bacteria, probiotics, can change the intestinal flora of patients with cancer of the colon. These are the findings of a study published in the journal BMJ Open Gastroenterology. “The probiotic strains used in this study are a promising positive factor for the continued development of treatments for colon cancer,” confirms Yvonne Wettergren, Associate...
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Bioinformatics points the way to treating deadly pancreatic cancer
A new study that sifted through an enormous mass of biomolecular data has significantly advanced our understanding of the genetics of pancreatic cancer and opened up promising treatment avenues. More than 40,000 Americans die each year from this devastating disease, making it the third deadliest cancer nationwide. Most patients do not show signs of the illness...
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Cancer vaccines need to target T cells that can persist in the long fight against cancer
Cancer vaccines may need to better target T cells that can hold up to the long fight against cancer, scientists report. Pictured is Dr. Yukai He. Cancer vaccines may need to better target T cells that can hold up to the long fight against cancer, scientists report. Studies of two T cell types that...
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Ludwig Scientists Discover Complex Axis of Immune Suppression Exploited by Cancers
A Ludwig Cancer Research study has uncovered a new mechanism by which cancer cells evade destruction by the immune system. The paper, led by Camilla Jandus of the Lausanne Branch of the Ludwig Institute for Cancer Research, describes how immune cells known as group 2 innate lymphoid cells (ILC2s) are recruited by leukemic cells to...