New research conducted at the stem cell centre, DanStem, at the University of Copenhagen shows that insulin is a key determinant of embryonic stem cell potency in mammals New research conducted at the stem cell centre, DanStem, at the University of Copenhagen shows that insulin is a key determinant of embryonic stem cell potency in...
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Production of key diabetes cells can be improved
Beta cells release insulin in your blood, but when you suffer from Type 1 diabetes, you hardly have any of them left in your body. This is because the immune system attacks the beta cells. The role of insulin is to reduce and regulate the blood sugar level when it is too high. People with...
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A ‘social control’ system guarantees embryonic stem cell purity
The CNIC research team has devised a novel image analysis tool that allows groups of pluripotent cells to be tracked according to the level of Myc in each cell A sophisticated system of ‘social control’ operating between neighboring cells allows embryos to protect the purity of their pluripotent cell population, which is able to generate...
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Contribution of transcranial magnetic stimulation to assessment of brain connectivity and networks
The goal of this review is to show how transcranial magnetic stimulation (TMS) techniques can make a contribution to the study of brain networks. Brain networks are fundamental in understanding how the brain operates. Effects on remote areas can be directly observed or identified after a period of stimulation, and each section of this review...
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How ketogenic diets curb inflammation
Ketogenic diets – extreme low-carbohydrate, high-fat regimens that have long been known to benefit epilepsy and other neurological illnesses – may work by lowering inflammation in the brain, according to new research by UC San Francisco scientists. The UCSF team has discovered a molecular key to the diet’s apparent effects, opening the door for new...
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Researchers identify new target, develop new drug for cancer therapies
A model of Penn’s new approach using DQ611 to target PPT1, which inhibits both mTOR and autophagy. Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past...
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StimTrack: An open-source software for manual transcranial magnetic stimulation coil positioning
1. Introduction Transcranial magnetic stimulation (TMS) is a non-invasive and painless technique to stimulate the human brain with an electromagnetic coil placed on the scalp. TMS is widely used as a tool to assess corticospinal excitability, a commonly used marker for corticospinal plasticity (Hallett, 2000). With the coil placed over the primary motor cortex a twitch in a contralateral muscle...
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A quick jab could reduce stroke damage
A Perth treatment could significantly reduce the damage done to brain cells following a stroke. Diego Milani from the University of Notre Dame Australia has been testing a new compound that has been shown to reduce damage in the brain after a stroke. The compound is made up of 18 molecules of the amino acid arginine...
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Is this the Alzheimer’s gene? Scientists find gene that raises risk of condition 12-fold
Researchers from Washington University School of Medicine in St. Louis studied the gene ApoE4 and its impact on the brain The mutant gene was discovered in 1993 and has been a mystery since for how it causes an increase in Alzheimer’s for people It is linked to brain damage from knots of protein in the...
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Psychosis in Parkinson’s dementia—new treatment provides hope
New research involving King’s College London and the University of Exeter has highlighted the benefits of a promising new treatment which could relieve psychosis in thousands of people with dementia related to Parkinson’s disease. Around 80 per cent of people with Parkinson’s disease develop dementia, totalling around 100,000 people in the UK. ,The majority of these...