Doctors say Mirabegron could provide an alternative for one in three men Drug works by relaxing muscles in the penis, allowing more blood to flow to it Erectile dysfunction is a common problem, often effecting men in middle age Can occur as result of vascular issues, such as high blood pressure and diabetes A...
Year: <span>2017</span>
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Controlling CRISPR: Researchers May Have Found An “Off-Switch” for Gene-Editing
IN BRIEF Researchers have uncovered two distinct anti-CRISPR proteins — AcrIIA2 and AcrIIA4 — that worked to inhibit the ability of SpyCas9 to target specific genomes in bacteria. The discovery could lead to an “off switch” for CRISPR that would give scientists greater control over the gene editing tool when using it in human subjects....
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Could new bone-forming growth factor reverse osteoporosis?
Scientists at the Children’s Medical Center Research Institute at UT Southwestern in Dallas, TX, have uncovered a new bone-forming growth factor that may reverse the bone loss associated with osteoporosis. They say that this discovery has implications for regenerative medicine. Osteolectin has been shown to promote bone growth in postmenopausal mice. Osteoporosis develops over several...
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Promising Study Results for Diabetic Kidney Disease Seen with Mesoblast’s Cell Therapy
Mesoblast recently announced positive results from the placebo-controlled Phase 2 trial of its cell therapy MPC-300-IV for diabetic kidney disease patients. All results can be found in the paper “Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo Controlled, Dose Escalation Study,” published in the journal EBioMedicine. The clinical trial, conducted by researchers at the University...
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Can a gel made with you own blood heal chronic leg wounds? Patients’ own DNA can help kickstart repair mechanisms in the body
A large proportion of chronic wounds treated by the NHS are diabetic foot ulcers The new gel aims to close ulcers that have failed to heal for months or even years Initial results suggest nine out of ten unhealed wounds responded to the new gel A gel made from a cocktail of the patient’s...
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Important element of immune defense against fungal infections discovered
Fungal infections are a serious health risk. They can be harmful especially to patients whose immune system is compromised through illness or chemotherapy. Scientists have discovered an important mechanism in the body’s defenses against fungi. The discovery explains, among other things, why people with certain genetic variations are more susceptible to fungal infections. To fight...
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Scientists discover the gene editing ‘off-switch’ that could protect against accidents or stop it from being used for harm
Researchers found proteins that are ‘potent inhibitors’ against Crispr-Cas9 Anti-Crispr proteins make procedure more precise to prevent an accident And, it would also provide a ‘fail safe’ if the technology falls in the wrong hands In recent years, the use of gene editing techniques has raised concern among both scientists and the public, with some...
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CAR-T Cell Therapy Effective Against Aggressive Brain Tumors, Say City Of Hope Researchers
A patient has been successful treated from recurrent multifocal glioblastoma through the means of CAR-T therapy. The method involves a specific kind of immunotherapy which targets cells where the IL13Rα2 antigen is present. The antigen is very common when it comes to brain cancer. Published in the New England Journal of Medicine on Dec. 29, the study...
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Sound used to detect unsound brains
To check if someone is concussed, seeing how their brain responds to sound may be the way to go(Credit: el.doctore/Depositphotos) If an athlete receives a concussion, there’s no question that they should receive medical attention as soon as possible. What can be harder to tell, however, is whether or not they’ve actually got a concussion. In the recent...
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Artists may unknowingly paint a picture of cognitive decline
Fractals in brush strokes may say a lot about the artist’s state of health(Credit:agencyby/Depositphotos) It’s not abnormal for the style of artists to evolve over time, but could very subtle changes represent something bigger than simply maturing tastes? Researchers at the University of Liverpool think they could. They’ve studied brushstrokes in thousands of paintings from...