IMAGE: THIS IS ULF YRLID, ASSOCIATE PROFESSOR, SAHLGRENSKA Groundbreaking discoveries regarding the onset of cholera are paving the way for a future, fast-acting antidote for cholera epidemics, according to research published in the journals PLOS Pathogens and ACS Infectious Disease. “This is not about a vaccine but rather a drinkable protection that can be distributed during an ongoing cholera...
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Programming DNA to deliver cancer drugs
New technology could lead to the development of new cancer therapies DNA has an important job–it tells your cells which proteins to make. Now, a research team at the University of Delaware has developed technology to program strands of DNA into switches that turn proteins on and off. UD’s Wilfred Chen Group describes their results...
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At first blush, you look happy—or sad, or angry We can read each other’s emotions from surprisingly tiny changes in facial color, study finds
COLUMBUS, Ohio—Our faces broadcast our feelings in living color—even when we don’t move a muscle. That’s the conclusion of a groundbreaking study into human expressions of emotion, which found that people are able to correctly identify other people’s feelings up to 75 percent of the time—based solely on subtle shifts in blood flow color around...
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Antibiotics could be key to relieving chronic bladder pain
Women suffering from recurrent cystitis or chronic bladder pain could benefit from a long-term course of antibiotics Antibiotics can successfully help rid a patient of chronic urinary tract infection symptoms. This is the finding of a new clinical study led by Sheela Swamy of University College London in the UK. The study in the International Urogynecology...
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Tamoxifen and raloxifene slow down the progression of muscular dystrophy
Long-term treatment with selective estrogen receptor modulators (SERMs) improves muscle, respiratory, and skeletal function without weakening bone in new mouse studies, according to a new report in The American Journal of Pathology Philadelphia, March 20, 2018 – Steroids are currently the only available treatment to reduce the repetitive cycles of inflammation and disease progression associated...
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Archived drug prevents Duchenne Muscular Dystrophy muscle loss in mice
A drug that showed promise in clinical trials for Duchenne Muscular Dystrophy (DMD) decades ago is back under the microscope and has now been shown to reduce muscle wasting in mice. DMD is an incurable, fatal disease that affects mainly boys, at a rate of one in 5,000 globally. Sufferers are usually wheelchair-bound by early adolescence....
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Metabolite therapy proves effective in treating C. difficile in mice
This photograph depicts Clostridium difficile colonies after 48hrs growth on a blood agar plate; Magnified 4.8X. C. difficile, an anaerobic gram-positive rod, is the most frequently identified cause of antibiotic-associated diarrhea (AAD). …more A team of UCLA researchers found that a metabolite therapy was effective in mice for treating a serious infection of the colon known...
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Chronic fatigue syndrome possibly explained by lower levels of key thyroid hormones
Overview of the study methods and results, which demonstrate a link between chronic fatigue syndrome symptoms and lower thyroid hormone levels Credit: © 2018 Ruiz-Núñez, Tarasse, Vogelaar, Dijck-Brouwer and Muskiet. Front. Endocrinol. doi: 10.3389/fendo.2018.00097 New research demonstrates a link between chronic fatigue syndrome (CFS) symptoms and lower thyroid hormone levels. Published in Frontiers in Endocrinology, the study...
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Electrical brain stimulation could benefit children with cerebral palsy, study finds
Every so often, Hadley Lucca will spend hours in front of her bedroom mirror, struggling to put on earrings or pull her long, golden locks back into ponytails. For Hadley, 11, activities that other girls her age take for granted can sometimes seem insurmountable. As an infant, she survived a stroke that resulted in hemiplegia,...
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Stem cell transplants are a ‘game changer’ for MS patients: Trial shows the pioneering method can stop the debilitating disease in its tracks
More than 100 patients with a common form of MS were involved in the study They were either given a stem cell transplant or were given conventional drugs The £30,000 treatment involves flooding the immune system with cancer drugs The immune system is then rebooted with stem cells from the MS patient’s blood Stem cell...